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Bitterroot Bio Announces Dosing of First Participants in a Phase 1, First-in-Human Study of BRB-002 in Healthy VolunteersPALO ALTO, Calif. and MELBOURNE, Australia, April 29, 2024 (GLOBE NEWSWIRE) -- Bitterroot Bio, a leader in developing innovative medicines in the field of cardio-immunology, today announced that the first human participants have been dosed in a Phase 1 study of BRB-002 in healthy volunteers. BRB-002 is a novel protein therapy targeting CD47 that is being investigated as a potential treatment option for patients with atherosclerotic cardiovascular disease (ASCVD). The Phase 1 trial is evaluating the safety and tolerability of subcutaneously administered BRB-002 in healthy volunteers. Bitterroot Australia Pty Ltd, a wholly owned subsidiary of Bitterroot Bio, Inc., is directing this clinical trial in partnership with the Nucleus Network in Brisbane. "The initiation of this Phase 1 trial is a vital step forward in our mission to address unmet cardiovascular needs, and marks Bitterroot’s transformation into a clinical-stage company," said Craig Basson, MD, PhD, Chief Medical Officer of Bitterroot Bio. "This milestone reflects our team's hard ork and dedication to advancing cardiovascular science by developing a novel medicine in ASCVD. We are optimistic about the potential of BRB-002 to make a meaningful difference in the lives of patients and are committed to rigorously evaluating its safety and efficacy in the clinic." About BRB-002 About Bitterroot Bio For more information, please visit https://www.brbio.com Media Contact: |