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Result of Annual General Meeting
[May 31, 2019]

Result of Annual General Meeting


NEW YORK, May 31, 2019 (GLOBE NEWSWIRE) -- Motif Bio plc (AIM/NASDAQ: MTFB), a clinical-stage biopharmaceutical company specialising in developing novel antibiotics, announces that at the Annual General Meeting held earlier today, all but one of the resolutions proposed were duly passed by the shareholders on a poll.

The Board notes that resolution 2, an advisory resolution on the directors’ remuneration report, was not passed. The Board is committed to remaining aligned with shareholder interests through its remuneration structures which are in place to recruit and retain talent.

The results of the poll, incorporating the proxy votes lodged in advance of the meeting, will shortly be available on the Company's website at: https://www.motifbio.com/.

The full text of the resolutions may be found in the Notice of the Annual General Meeting, copies of which are available on the Company's website https://www.motifbio.com/.

For further information please contact:

Motif Bio plcir@motifbio.com
Graham Lumsden (Chief Executive Officer) 
  
Walbrook PR Ltd. (UK FINANCIAL PR & IR)+44 (0)20 7933 8780
Paul McManus/Lianne Cawthorne/Helen Cresswellmotifbio@walbrookpr.com
  
Peel Hunt LLP (NOMAD & JOINT BROKER)+ 44 (0)20 7418 8900
Dr Christopher Golden 
Oliver Jackson 
  
SP ANGEL CORPORATE FINANCE LLP (JOINT BROKER)+44 (0)20 3470 0470
David Hignell/ Vadim Alexandre /Rob Rees 
  
MC Services AG (EUROPEAN IR)+49 (0)89 210 2280
Raimund Gabrielraimund.gabriel@mc-services.eu
  
LifeSci Advisors (U.S. IR)+1 (646) 597 6989
Bob Yedidbob@lifesciadvisors.com
  
Russo Partners (U.S. PR)+1 (858) 717 2310 or +1 (212) 845 4272
David Schull  david.schull@russopartnersllc.com



Note to Editors:

About Motif Bio


Motif Bio plc (AIM/NASDAQ: MTFB) is a clinical-stage biopharmaceutical company focused on developing novel antibiotics designed to be effective against serious and life-threatening infections caused by multi-drug resistant Gram-positive bacteria, including MRSA. The Company’s lead product candidate is iclaprim. Motif Bio is seeking approval of iclaprim from the U.S. Food & Drug Administration (FDA) for the treatment of acute bacterial skin and skin structure infections (ABSSSI). More than 3.6 million patients with ABSSSI are hospitalised annually in the U.S. It is estimated that up to 26% of hospitalized ABSSSI patients have renal impairment.

The Company also has plans to develop iclaprim for hospital acquired bacterial pneumonia (HABP), including ventilator associated bacterial pneumonia (VABP), as there is a high unmet need for new therapies in this indication.  A Phase 2 trial in patients with HABP has been successfully completed and a Phase 3 trial is being planned. Additionally, iclaprim has been granted orphan drug designation by the FDA for the treatment of Staphylococcus aureus lung infections in patients with cystic fibrosis and is in pre-clinical development for this indication.

Iclaprim received Qualified Infectious Disease Product (QIDP) designation from the FDA together with Fast Track status for the ABSSSI indication. If approved for the ABSSSI indication as a New Chemical Entity, iclaprim will be eligible for 10 years of market exclusivity in the U.S. from the date of first approval, under the Generating Antibiotic Incentives Now Act (the GAIN Act). In Europe, 10 years of market exclusivity is anticipated.  Motif is also building a patent estate to provide additional protection for iclaprim and has two U.S. method of use patents issued that will expire in 2037.

Forward-Looking Statements

This press release contains forward-looking statements. Words such as “expect,” “believe,” “intend,” “plan,” “continue,” “may,” “will,” “anticipate,” and similar expressions are intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that may cause Motif Bio’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Motif Bio believes that these factors include, but are not limited to, (i) the timing, progress and the results of clinical trials for Motif Bio’s product candidates, (ii) the timing, scope or likelihood of regulatory filings and approvals for Motif Bio’s product candidates, (iii) Motif Bio’s ability to successfully commercialise its product candidates, (iv) Motif Bio’s ability to effectively market any product candidates that receive regulatory approval, (v) Motif Bio’s commercialisation, marketing and manufacturing capabilities and strategy, (vi) Motif Bio’s expectation regarding the safety and efficacy of its product candidates, (vii) the potential clinical utility and benefits of Motif Bio’s product candidates, (viii) Motif Bio’s ability to advance its product candidates through various stages of development, especially through pivotal safety and efficacy trials, (ix) Motif Bio’s estimates regarding the potential market opportunity for its product candidates, (x) Motif Bio’s ability to raise additional capital to sustain its operations and pursue its strategy and (xi) the factors discussed in the section entitled “Risk Factors” in Motif Bio’s Annual Report on Form 20-F filed with the SEC on April 15, 2019, which is available on the SEC’s web site, www.sec.gov. Motif Bio undertakes no obligation to update or revise any forward-looking statements.

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