[March 29, 2018]

Market Spotlight: Attention Deficit Hyperactivity Disorder (ADHD) Report 2018 - ResearchAndMarkets.com

The "Market Spotlight: Attention Deficit Hyperactivity Disorder (ADHD)?" report has been added to ResearchAndMarkets.com's offering.

This Market Spotlight report covers the Attention Deficit Hyperactivity Disorder (ADHD) market, comprising key pipeline and marketed drugs, clinical trials, upcoming and regulatory events, patent information, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.

Key Takeaways

• The author estimates that in 2016, there were 175.1 million prevalent cases of attention deficit hyperactivity disorder (ADHD) in people aged 5-44 years worldwide, and forecasts that number to increase to 185.5 million prevalent cases by 2025.
• The worldwide prevalence of ADHD among children aged 5-19 years is estimated to be 5.29%, while the prevalence among adults aged 20-44 years is estimated to be 2.80%.
• The majority of approved drugs in the ADHD space target dopamine, dopamine reuptake, norepinephrine (noradrenaline), norepinephrine (noradrenaline) reuptake/transporter, and alpha 2 adrenergic receptors. Most of the drugs are commonly administered via the oral route, however, a few products are available in topica and intranasal formulations.
• The majority of industry-sponsored drugs in active clinical development for ADHD are in Phase II. Therapies in mid-to-late stage development for ADHD focus on a wide variety of targets. Among these therapies, Benjorna (methylphenidate) is closest to market. The majority of the pipeline drugs in mid-to-late-stage development for ADHD are administered via the oral route.
• High-impact upcoming events for drugs in the ADHD space include the US Food and Drug Administration's decision on NDAs for Benjorna and dasotraline, and topline Phase II results for AEVI-001.
• There were 14 licensing and asset acquisition deal agreements during 2013-17. Impax Laboratories' acquisition of certain assets related to generic products from Teva and Allergan, for $586m, was the largest deal during the period.
• Vyvanse's (lisdexamfetamine dimesylate) sales have ranked highest in the ADHD space during 2012-16 and are forecast to remain the highest during the forecast period (2017-22).
• The clinical trials distribution across Phase I-IV indicates that there is an even distribution of trials for ADHD, with 45.5% of trials in Phase I-II, and 54.5% in Phase III-IV.
• The US has a substantial lead in the number of ADHD clinical trials globally. Germany leads the major EU markets, while Japan has the top spot in Asia.
• Clinical trial activity in the ADHD space is dominated by completed trials. Shire has the highest number of completed clinical trials for ADHD, with 144 completed trials.
• Shire has carried out the most Phase III trials in ADHD, followed by Eli Lilly, which has sponsored 50 Phase III trials.

1 Key Takeaways

2 Disease Background

3 Treatment

4 Epidemiology

5 Marketed Drugs

6 Pipeline Drugs

7 Key Upcoming Events

8 Licensing And Asset Acquisition Deals

9 Parent Patents

10 Revenue Opportunity

11 Clinical Trial Landscape

12 Bibliography

For more information about this report visit https://www.researchandmarkets.com/research/st9zxt/market_spotlight?w=4

View source version on businesswire.com: https://www.businesswire.com/news/home/20180329005493/en/

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