TMCnet News
DNA Sequencing Markets: Global Analysis and Opportunity Evaluation 2016 - 2020NEW YORK, Jan. 30, 2017 /PRNewswire/ -- This market report gives a comprehensive and easy-to-review analysis of the DNA sequencing market 2016 – 2020. It provides key market data and identifies new and emerging opportunities across this growing field. The analysis is based on primary data disclosed by experienced end-users' on their current sequencing practices and their plans over the next three. Its findings provide a wealth of market information on the sequencing market and enables suppliers to reduce costs, identify new markets and compete more effectively in the global marketplace. Gene variants in disease, Genetic mapping, Genome Resequencing, Genotyping by Sequencing, Genotyping of microorganisms, Haplotypes, Immune diversity, Metagenomics, Methylation Sequencing, Microbial Sequencing, MicroRNA Studies, Microsatellites, Phylodynamic analyses, Rapid Diagnostic - Genetic Markers, Regulatory elements, Ribosomal DNA (rRNA) Studies, RNA Sequencing, Short Tandem Repeat Analysis, Single Nucleotide Polymorphisms, Single-Strand Conformation Polymorphism, Small insertions or deletions, Small Interfering RNA (siRNA) Studies, Small Nuclear RNA (snRNA) Studies, Small RNA and miRNA Sequencing, Targeted DNA sequencing, Targeted Resequencing, Tissue typing, Total RNA Sequencing (Transcriptome), Transfer RNA (tRNA) Studies, Ultra-Low-Input/Single-Cell RNA-Seq, Viral Typing, Whole-Genome Sequencing and any others. Clonal Amplification: End-users' clonal amplifications methods used in their nucleotide sequencing, both currently and anticipated in three years, where the methods considered were Bridge PCR Amplification, Emulsion PCR Amplification, Rolling Circle Amplification and None (e.g. Single Molecule Sequencing). Diseases: End-user's current sequencing activities, and those sequencing activities they anticipate in three years from now, relating to specific disease areas, namely Antimicrobial resistance, Arthritis, Asthma and allergy, Autoimmune Diseases, Bone Metabolism, Cancer, Cardiovascular, Central Nervous System, Dentistry, Dermatology, Endocrine, Gastrointestinal, Genetic diseases, Genito-Urinary System, Haematology, Hearing Loss, Immunodeficiency, Infections, Infertility, Inflammation, Liver disease, Metabolic Disorders, Musculoskeletal Disorders, None, Nutrition, Obstetrics and Gynaecology, Ophthalmology, Pain, Phytopathology, Psychiatry, Rare diseases, Reproduction, Respiratory, Sexually transmitted infections, Skin, Stem cells, Transplantation medicine, Vector borne disease, Virus diseases and any others. Nucleotide Types: Main nucleic acid types currently sequenced, as well as those anticipated to be sequenced in three years from now, where the nucleic acids considered were Archaeal DNA, Bacterial DNA, Bacterial PCR amplicons, Bisulfite-converted DNA, cDNA, cell free miRNA, fungal DNA, Genomic DNA, ITS region, Metagenomic DNA, MicroRNA, Mitochondrial DNA, mRNA, Noncoding RNA, Nuclear DNA genes, Pathogen RNA/DNA, piRNA, Plant viral RNA or DNA, Plasma Cell Free DNA, Plasmid DNA, Prokaryotic small RNA, Protist DNA, Ribosomal RNA (rRNA), Small interfering RNA (siRNA), Small nuclear RNA (snRNA), Total RNA, Transfer RNA (tRNA), Tumour Cell DNA, Viral DNA, Viral PCR amplicons, Viral RNA and any others. Software: Sequencers main software programs used for their nucleotide sequencing activities and those considered (n = 387) were ABA (Raphaelet al.), ABySS (Simpson et al.), ACANA (Huang et al.), ACT (Sanger), Alamut (Interactive Biosoftware), ALE (Blandy et al.), AlignMe (Stamm et al.), ALLPATHS (Broad Institute), Alta-cyclic (Omictools), AMAP (Schwartz et al.), AnnHyb (MyBiosoftware), Annovar (Open Bioinformatics), anon. (Powell et al.), Answer Choices , Artemis (Sanger), Augustus (Göttingen), AVID (Vista), BAliBASE (Thompson et al.), BAli-Phy (Redelings et al.), BarraCUDA (GPL), Base-By-Base (Brodie et al.), BBMap (Source Forge), Beast (Drummond et al.), Belvu (Sanger), BFAST (GPL), BigBWA (Omictools), Bioconductor (Aboyoun et al.), BioEdit (Ibis), BioLinux (EON), Biomart (Ensembl), BioNumerics (Applied Maths), BioPerl dpAlign (Chan et al.), Biopieces (Biostars), BisMark (Babraham), BLAST (Altschul et al.), BLASTN (NCBI), BLASTZ,LASTZ (Schwartz et al.), BLAT (Non-Commercial Academic), BLOCKS (Molbio-Tools), Bowtie (Artistic License), BS-Seq (UCLA), Bustard (Illumina), BWA (GPL), BWA-PSSM (Bio-BWA), Cap3 (Genome), Casava (Illumina), CASHX (Non-Commercial Academic), CEQ (Beckman et al.), CHAOS/DIALIGN (Brudno et al.), ChIP-Seq (DNASTar), Chromas (Technelysium), Clarity (Genologics), CLC Genomic Workbench (CLCBio), Clone Manager (CLCBio), Cloudburst (Artistic License), ClustalW (Thompson et al.), CNVnator (Omictools), CNV-Seq (Chao et al.), CodonCode Aligner (Richterich et al.), Compass (Sadreyev, et al.), Contig Express (Contig), CS-BLAST (Angermueller et al.), CUDA-EC (Omictools), CUDAlign (Source Forge), CUDA-MEME (MyBiosoftware), CUDASW++ (Liu et al.), Cufflinks (Cole-trapnell), CUSHAW (GPL), CUSHAW2 (GPL), CUSHAW2-GPU (GPL), CUSHAW3 (Source Forge), Custom Designed (In-House), Dalliance (Omictools), dbSNP (Open Source), DECIPHER (DecipherProject), DESeq (Bioconductor), DIALIGN-TX and DIALIGN-T (Subramanian et al.), DIAMOND (GitHub), DNA Alignment (Roehl et al.), DNA Baser Sequence Assembler (Heracle BioSoft), DNADot (Bowen et al.), DNAsp (UBEdu), DNASTAR (DNAStar), DOTLET (Pagni et al.), dpAlign (BioPerl), drFAST (BSD), EagleView (Boston College), Edena (Hernandez ), EDNA (Salama et al.), ELAND (Illumina), EMBL-EBI (EBI Ac), eMOTIF (Stanford), Ensemble (Ensembl), ERANGE (Wold Lab), ERNE (GPL), EULER-SR (Chaisson ), Excel (Open Source), Exonerate (Guy St C Slater et al.), ExpressionSuite (Thermo Fisher), FASTA (Faster Biotech), Fastpcr (PrimerDigital), FastQC (Babraham), fastseq (Helical), fastx-tools (Hannon), FEAST (Hudek et al.), FindPeaks (Bainbridge et al.), FMM (Open Source), FreeBayes (Omictools), FSA (Bradley et al.), Galaxy (Galaxy), GapMis (Frousios et al.), GASSST (Omictools), GATK (Broad Institute), GEM (Non-Commercial Academic), GenAlex (BiologyAssets), Genalice MAP (Genalice), GenDB (Open Source), Gene Construction Kit (Textco), Gene Mapper (ABI), Gene tex (Genetex), GeneInsight (Geneinsight), Geneious (Drummond et al.), Geneious Assembler (Geneious), GeneMapper® Software (ABI), Genologics (Illumina), Genomatix (Genomatix), Genome Browser (UCSC), Genome Compiler (Genome Compiler), GenomeMapper (1001 Genomes project), GenomeStudio Software (Illumina), Genomics Workbench (CLCBio), Genoogle (Genoogle), Genotyper (ABI), GenSearch (Phenosystems), GensearchNGS (Omictools), Geospiza (Geospiza et al.), GGSEARCH, GLSEARCH (Pearson et al.), Gibbs motif sampler (Omictools), Glimmer (CBCD), GLProbs (Omictools), GMAP and GSNAP (Non-Commercial Academic), G-Mo.R-Se (CNS, France), GNUMAP (Omictools), G-PAS (Frohmberg et al.), GS Amplicon Variant Analyzer (Roche), HapCompass (Omictools), HGMD (Biobase), HHpred / HHsearch (Söding et al.), HiSeq Software (Illumina), HIVE-hexagon (Hive), HMMER (Durbin et al.), HMMTOP (SACS), HOMSTRAD (Mizuguchi et al.), Htseq (Huber et al.), HyPhy (Hyphy et al.), Ibis (Ibis), IDF (CSUni), IGV (Broad Institute), IMEX (Omictools), IMGT (IMGT), Infernal (Eddy), Ingenuity (Ingenuity), In-House (In-House), Ion Reporter (Thermo Fisher), Ion torrent (Thermo Fisher), iSAAC (Non-Commercial Academic), I-sites (Open Source), JAligner (Moustafa et al.), Jalview (Jalview), JCoils (CHEmbnet), K*Sync (Chivian et al.), Kalign (Lassmann et al.), KLAST (CLCBio), Kodon (Applied Maths), LALIGN (Pearson et al.), Lasergene (DNAStar), LAST (GPL), LASTZ (NCBI), LookSeq (Sanger), MACS (Zhang et al. ), MacVector (MacVector), MAFFT (Katoh et al.), Mage Platform (Genoscope), mAlign (Powell et al. ), Manattee (Manattee), MapNext (Sun-Yat Sen Univ), MapView (Sun-Yat Sen Univ), MAQ (GPL), MARNA (Siebert et al.), Matcher (Longden et al.), Mauve (Darlinglab), MAVID (Bray et al.), MCALIGN2 (Wang et al.), MEGA (Megasoft), MEME/MAST (Meme), MERCI (Bioinfo), Metacore (Omictools), MG RAST (Metagenomics), MGA (Omictools), Mira (Omictools), MIRA2 - MIRA (Source Forge), MirCheck (Mybiosoftware), Mirdeep2 (MDC Berlin), miREvo (Omictools), MiSeq (Illumina), MiSeq Software (Illumina), MOM (CS.CMU), MOSAIK (Strömberg et al. ), Mothur (Mothur), MPscan (Omictools), MrBayes (MrBayes), mrFAST and mrsFAST (BSD), MSA (Lipman et al.), MSAProbs (Liu et al.), MSeqDR (Open Source), Mulan (Mulan), MULTALIN (Corpet et al.), Multi-LAGAN (Brudno et al.), Multiz (Mybiosoftware), MUMmer (Kurtz et al.), MUSCLE (Edgar et al.), Mutation Surveyor (Softgenetics), mVista (Genome), MyRAST (Mybiosoftware), NCBI (Open Source), Needle (Bleasby et al.), NETGLYC (CBS), NetPrimer (PremierBiosoft), Newbler (Roche), NextGENe (Softgenetics), NextGenMap (Omictools), Ngila (Cartwright et al.), NISC (NIH), Novoalign & NovoalignCS (Non-Commercial Academic), NW-align (Zhang et al.), Omixon (Omixon), Opal (Wheeler et al.), Oxbench (Raghava et al.), PAL_finder (Source Forge), PALMapper (GPL), Pandaseq (Github), Panther (Omictools), Parasail (BMC), Partek (Partek), Pasa (Pasa), PASS (CRIBI), Path (Gîrdea et al.), PathSeq (Broad Institute), PatternHunter (Ma et al.), PAUP (Evolution), PeakSeq (Rozowsk et al.), Pecan (Paten et al.), PerM (GPL), PFAM (Sanger), PHI-Blast (NCBI), Phylo (McGill Bioinformatics), Phylogeny (Evolution), Phyloscan (NCBI), phyML (ATGC), Picard (Broad Institute), PicXAA (Omictools), PLAST-ncRNA (NCBI), PMS (Open Source), POA (Lee et al.), PolyBayesShort (Boston College), Polyphen (Harvard), Praline (Heringa et al.), PRATT (EBI Ac), PREFAB (Edgar et al.), Primer 3 (PremierBiosoft), PRIMEX (Open Source), Prism (ABI), ProbA (also propA) (Mückstein et al), Probalign (Roshan et al.), ProbCons (Do et al.), Prodigal (Omictools), PROMALS3D (Pei et al.), Proseq (Biosoft), PRRN/PRRP (Totoki et al), PSAlign (Sze et al.), PSI-BLAST (Altschul et al. ), PSI-Search (Li et al.), PyMOL (DeLano et al.), PyroBayes (Boston College), Python (DigitalBiol), QIIME (QIIME), Qpalma (De Bona et al. ), QuEST (Stanford), R (Open Source), RAST (Molbiotools), Ray (Denovo), RazerS (LGPL), RDP (NCBI), REAL, cREAL (GPL), REPuter (Kurtz et al.), Responses , Responses , RevTrans (Wernersson et al.), RMAP (GPL), rNA (GPL), RNASAT (Stanford), Rolexa (Bioconductor), RTG Investigator (Non-Commercial Academic), SABERTOOTH (Teichert et al.), SABmark (Van Walle et al.), SAGA (Notredame et al.), SAM (Krogh et al.), Satsuma (Grabherr et al.), ScalaBLAST (Oehmen et al.), ScanProsite (Prosite), Se-Al (Rambaut et al.), Seaview (Mybiosoftware), Segemehl (Non-Commercial Academic), SEQALN (Waterman et al.), SEQAN (Rausch et al.), SeqMan (DNAStar), SeqMap (Jiang et al.), SeqScape (Thermo Fisher), Sequence Scanner Software (ABI), Sequences Studio (Meskauskas et al.), Sequencher (Gene Codes Corp), Sequencing Analysis Software (ABI), Sequencing Analysis Viewer (Illumina), Sequerome (Bioinformatics.org), Sequilab (Lifescisoft), Serial Cloner (SerialBasics), SHARCGS (Dohm et al.), SHORE (1001 Genomes project), Shrec (Omictools), SHRiMP (Brudno et al.), Shuffle-LAGAN (Stanford), SIBsim4 / Sim4 (NEBC), SIM, GAP, NAP, LAP (Huang et al.), SISSRs (Jothi et al.), Slider (BCGSC), SlimSearch (EdwardsLab), SMART (Letunic et al.), SOAP, SOAP2, SOAP3 and SOAP3-dp (GPL), SOCS (Ondov et al.), SOLiD™ Software (ABI), SPA (Shen et al), SPAdes (Open Source), Splign (Open Source), SSAHA and SSAHA2 (Non-Commercial Academic), SSAKE (Omictools), SSEARCH (Pearson et al.), Staden (Source Forge), Stampy (Non-Commercial Academic), StatAlign (Novak et al.), Stemloc (Holmes et al.), SToRM (Omictools), stretcher (Longden et al.), Subread and Subjunc (GPL), SureCall (Agilent), SWAPHI (Open Source), SWAPHI-LS (Open Source), SWIFT suit (Rasmussen et al.), SWIPE (GNU), SXOligoSearch (Synamatix), Syngene (GeneTools), Tablet (Omictools), Taipan (Non-Commercial Academic), T-Coffee (Notredame et al.), TEIRESIAS (IBM), TopHat (Univ's Maryland/California ), Torrent (Thermo Fisher), tranalign (Williams et al.), Trinity (Strozzi et al.), UCHIME (Mothur), UCLUST (NEBC), UGENE (GPL), USEARCH (Drive5), VarScan (Source Forge), VCAKE (Omictools), Vector NTI (Thermo Fisher), VectorFriends (BioFriends team), VelociMapper (Omictools), Velvet (Zerbino et al), Vmatch (VMatch ), water (Bleasby et al.), wordmatch (Longden et al.), XMatchView (Warren et al. ), XpressAlign (Non-Commercial Academic), YASS (Noe et al), Zenbu (Omictools), ZOOM (Omictools) and any Others. Sequencing Performance: Five areas of the performance of end-users' sequencing activities were investigated namely read length (bp) that they typically achieve in your sequencing work, the accuracy (%, single read, not consensus) that they believe they achieve in their work, the reads per run (in millions of bases) that they typically achieve in their work, the typical time per run (minutes, hours, days, weeks or months) in their sequencing work and the sequencing costs in terms of US$ per 1 million bases. Numbers of samples: Sequencers estimates of the number of study samples they sequence in their laboratory, where the options were <1; 1; 1 to 2; 2 to 3; 3 to 4; 4 to 5; 5 to 7; 7 to 10; 10 to 15; 15 to 25; 25 to 40; 40 to 60; 60 to 100; 100 to 150; 150 to 200; 200 to 250 or 250. >Disease Biomarkers: Sequencers were asked if they use sequencing to research, discover or measure disease biomarkers, where the options were yes or no. Those who answered yes to this question were asked to indicate indicate which disease biomarkers they study in their sequencing work. These included Absolute DNA quantification, Alternative spliced variants, Bacteria detection, DNA methylation, Gene copy number, Gene expression, Gene mutations/polymorphisms, Haplotypes, microRNA, Protein mRNA quantification, Single nucleotide polymorphisms (SNPs), Small interfering RNA, Small nuclear RNA, SSRs or TRs, Tissue typing, Virus detection or any others. Study samples: Sequencers were asked to indicate the main study samples in their sequencing activities where the options were Algal, Animal tissues, Archaeal cultures, Bacterial cultures, Bone, Cell isolates, Cells, Cerebrospinal fluid, Cultures, Dried blood, Embryos, Environmental samples, Faeces/Stools, Fermented foods, Foodstuffs, Fungal material, Genetic material, Human tissues, Insect material, In-vitro solutions, Isolated viruses, Marine, Marine invertebrates, Paraffin embedded tissue, , Phage material, Plant material, Plasma, Protozoa, Respiratory fluids, Saliva, Semen, Serum, Soil, Swabs, Teeth, Urine, Venom, Water, Whole blood or any others. Sample Preparation: Sequencers were asked to indicate the main sample preparation method(s) that they use in their sequencing activities, where the methods considered were solution-Phase Methods; Automated Solution-Phase Methods; Solid-Phase Methods; Automated Solid-Phase Methods or others. Sequencers were also asked to indicate if they used kit-based sample preparation products in your nucleotide sequencing activities. Those who did were invited to indicate their preferred suppliers. Advantages and disadvantages: Sequencers were asked to indicate that they considered to be the main advantages and disadvantages of their most commonly used nucleotide sequencing techniques. Fields: End-users' field or sector relating to their use of sequencing, including Bacteriology, Bioinformatics, Blood groups, Blood products, Cell research, Clinical research, Clinical trials, Conservation Genetics, Diagnostic screening, Diagnostics, Diagnostics research, Disease biomarkers, Disease research, Drug R&D, Drug targets, Environmental microbiology, Environmental tests, Evolutionary biology, Food monitoring, Forensics Genetics, Fundamental research, Genomics, Histology, HLA-Typing for transplantation, Immunology, Laboratory surveillance, Metagenomics, Microbiology, Mitochondrial DNA, Molecular Ecology, Molecular epidemiology, Molecular Systematics, Natural products, Parasitology, Paternity Testing, Phylogenetics, Plant Breeding, Plant Evolution, Plant Sciences, Population genetics, Preclinical research, Proteomics, Responses, Soil ecology, Taxonomy, Treatment monitoring, Virology and other. Role: End-user's main role relating to their use of nucleotide sequencing, where the options were Laboratory Scientist, Physician or Clinician, Laboratory or Clinical Manager, Veterinarian and Other. Organisation Type: End-users organisation type, where the options were Clinic, Government Organisation, Hospital, Large International Company, Medium Sized Company, Research Institute, Small Company, Teaching Hospital, University, Veterinary Organisation or other. Experience: End-users' years of experience using nucleotide sequencing. Job Title: End-user's job title. Countries and Regions: End-users' countries and global regions; Asia, North America, South America, Africa (Sub-Saharan), Central America/Caribbean, Australia, New Zealand and Oceania and Middle East/North Africa/and Greater Arabia. Participants: Names, organisation name and business email address. Read the full report: http://www.reportlinker.com/p04630503-summary/view-report.html About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place. http://www.reportlinker.com __________________________ Contact Clare: [email protected] US: (339)-368-6001 Intl: +1 339-368-6001 To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/dna-sequencing-markets-global-analysis-and-opportunity-evaluation-2016---2020-300399048.html SOURCE Reportlinker |