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BIOPHYTIS Announces Successful Completion of SARA-PK Clinical Study for Sarconeos in Sarcopenia Confirming Safety ProfileROMAINVILLE, France, Nov. 30, 2016 (GLOBE NEWSWIRE) -- BIOPHYTIS (Alternext Paris:ALBPS), a biotechnology company specialized in the development of drug candidates to treat aging diseases, announces the successful completion of its SARA-PK clinical study for Sarconeos, lead drug candidate for the treatment of sarcopenia. The results of the study, conducted in young and elderly healthy volunteers, confirmed Sarconeos’ appropriate safety profile, with no serious adverse events associated with the administration of Sarconeos. Stanislas Veillet, Chief Executive Officer of BIOPHYTIS, said: “The successful outcome of the SARA-PK study is an important milestone for BIOPHYTIS and our Sarconeos development program. We have strong confidence in Sarconeos’ safety profile and will move forward with our Phase 2b SARA-INT study in 2017, as planned. We believe Sarconeos is well differentiated and has significant potential to treat sarcopenia, a debilitating muscle wasting disease that is largely untreatable today.” The objective of the SARA-PK study was to assess the safety, tolerability and pharmacokinetic profile of Sarconeos in elderly healthy volunteers (> 65 years old). The study was conducted in two phases: single ascending dose (SAD) administration, and multiple ascending dose (MAD) administration. The MAD portion of the study was aimed at evaluating the safety and pharmacokinetics of Sarconeos in 30 older subjects, following three ascending oral administrations daily for 14 days (350mg/day, 700 mg/day then 900 mg/day). Both phases of the SARA-PK study have now been successfully completed. The results of the SARA-PK study will be used to select the two doses of Sarconeos for further evaluation in the Phase 2b SARA-INT trial, which BIOPHYTIS intends to initiate in the first half of 2017. The complete results of the SARA-PK study, in particular the pharmacokinetic profile of Sarconeos, will be available in the first quarter of 2017. Initial study results will be presented at the 9th International Conference on Sarcopenia, Cachexia, and muscle Wasting Diseases (SCWD), being held December 10-11, 2016, in Berlin, Germany. About SARCONEOS: About BIOPHYTIS: BIOPHYTIS is listed on the Alternext market of Euronext Paris BIOPHYTIS is eligible for the Equity Saving Plans PEA-PME. Disclaimer This press release and the information contained herein do not constitute an offer to sell or a solicitation of an offer to buy or subscribe to shares in BIOPHYTIS in any country. Items in this press release may contain forward-looking statements involving risks and uncertainties. The Company’s actual results could differ substantially from those anticipated in these statements owing to various risk factors which are described in the Company’s prospectus. This press release has been prepared in both French and English. In the event of any differences between the two texts, the French language version shall supersede.
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