[May 25, 2016]

Georgetown University's Innovation Center for Biomedical Informatics Adopts GenePool from Station X to Power Cancer Research

Station X, Inc., a pioneer in solving big data analytics and platform integration challenges for customers engaging in genomics-based clinical research and medical applications, today announced that the Innovation Center for Biomedical Informatics (News - Alert) (ICBI) at Georgetown University has adopted the company's GenePool platform for use in genomic research related to pancreatic cancer.

The Innovation Center for Biomedical Informatics (ICBI) was launched in 2012 as an academic hub for innovative research in the field of biomedical informatics with the goal of enabling more individualized approaches to health care based on patient genetics. ICBI's mission is to enhance translational research at Georgetown University Medical Center and, in turn, attract and educate the next generation of scientists and physicians for whom biomedical informatics will be an integral part of both research and clinical practice. ICBI's major activities are focused on areas that include precision medicine; biocuration and data coordinating centers; omics and bioinformatics; big data methods and technology; and medical informatics. For more information please visit icbi.georgetown.edu.

"Genomics and bioinformatics are central to realizing the promise of precision medicine and there is a pressing need for technologies that facilitate collaboration and bridge from foundational research to translational applications in the clinic," said Subha Madhavan, PhD, director of the ICBI. "GenePool will allow us to replace or augment a number of disparate tools with an integrated solution that can support basic research applications like molecular profiling and then, help us place those fidings within the context of individual patient datasets to support translational research and clinical decision making."

GenePool is an enterprise-level customizable and extensible multi-omics platform for biomarker discovery, translational research and clinical genomics. Built upon a modern cloud-based architecture with big data technologies, analytical and visualization tools, the platform is designed for storing, analyzing and managing patient data in a HIPAA compliant environment. GenePool is pre-loaded with reporting capabilities for incidental findings and tumor profiling, but its flexibility means organizations like ICBI can customize GenePool for use with their own reporting requirements. GenePool also provides a convenient and dynamic way to securely store variants of interest and their associated metadata for updated reporting and for investigating the aggregated information.

"GenePool integrates a wide range of data types with a modern and scalable analysis pipeline to accelerate the identification and validation of biomarkers that play a role in human disease," said Tod Klingler, Chief Scientific Officer of Station X. "ICBI's adoption of GenePool, combined with our growing user base across research, diagnostic and biopharma organizations, is an exciting validation of the platform and its ability to support large enterprises pursuing a variety of precision medicine applications."

Through GenePool, ICBI can aggregate genomic, biochemical, and clinical information from public and proprietary databases to further define molecular subtypes that they could use in the development of custom reports supported by the comprehensive analysis of rich and ever-growing content libraries such as The Cancer Genome Atlas (TCGA), ClinVar, COSMIC, dbSNP, FDA Pharmacogenomics Biomarkers, PharmaADME, and many others.

GenePool integrates with existing LIMS systems and leading third-party data storage and management platforms including Amazon Web Services (News - Alert), DNAnexus, Google Cloud Platform, Illumina BaseSpace, Microsoft Azure and Seven Bridges Genomics, among others.

For more information about GenePool, please visit www.stationxinc.com.

About Station X

Station X is a leading provider of cloud-based enterprise software solutions that are being used to solve big data analytics and platform integration challenges for customers utilizing genomic data in clinical research and medical applications. GenePool, our flagship product, provides a secure modern architecture that enables secure collaboration and streamlines the delivery of medically relevant insights via innovative solutions for managing and interpreting complex data. Leading academic and commercial organizations around the world are relying on Station X to help them deliver next-generation precision medicine solutions. For more information please visit www.stationxinc.com.

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