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Bharat Book Bureau: PharmaPoint: Hepatitis C Virus - Germany Drug Forecast and Market Analysis to 2022
[December 05, 2013]

Bharat Book Bureau: PharmaPoint: Hepatitis C Virus - Germany Drug Forecast and Market Analysis to 2022

(M2 PressWIRE Via Acquire Media NewsEdge) Summary "PharmaPoint: Hepatitis C Virus - Germany Drug Forecast and Market Analysis to 2022". Hepatitis C is a liver infection caused by the hepatitis C virus (HCV) that results in acute or chronic presentation. The disease is often asymptomatic, but infected patients may experience fatigue, joint pain, itchy skin or jaundice. There is no effective vaccine against HCV, so the market is driven by therapeutics. Currently, drug combinations containing pegylated interferon (e.g., Roche's Pegasys and Merck's PegIntron) and ribavirin (e.g., Roche's Copegus and Merck's Rebetol) are used to treat HCV infection. Patients infected with HCV genotype 1 can also have a protease inhibitor added to their combination therapy, such as Merck's Victrelis (boceprevir) or Vertex's Incivek (telaprevir). The entrance of next-generation HCV therapies is expected to fundamentally change the HCV treatment algorithm. GlobalData expects a dramatic shift favoring the uptake of interferon-free regimens due to their more tolerable side-effect profiles and decreased duration of therapy compared with the current standard of care.

GlobalData expects that factors such as HCV screening initiatives, increases in patient awareness, and the launch of next-generation HCV therapies will drive the growth of the HCV market in Germany.

Incivo was among the first DAA HCV regimens launched in German. The drug quickly captured market share due to its improved efficacy over the previous standard of care, a combination of peginterferon and ribavirin, for the most prevalent HCV genotype in Germany, HCV GT1. GlobalData believes that Incivo's shorter duration of triple therapy (i.e., co-administration of DAA, peginterferon, and ribavirin) enabled it to capture more market share than Merck's Victrelis, the other DAA launched around the same time as Incivo.

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