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U.S. Patents Awarded to Inventors in Maryland (May 24)(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., May 24 -- The following federal patents were awarded to inventors in Maryland. *** MacroGenics Assigned Patent ALEXANDRIA, Va., May 24 -- MacroGenics, Rockville, Md., has been assigned a patent (8,445,645) developed by five co-inventors for an "identification and engineering of antibodies with variant Fc regions and methods of using same." The co-inventors are Jeffrey Stavenhagen, Brookville, Md., Sujata Vijh, Gaithersburg, Md., Christopher Rankin, Clarksburg, Md., Sergey Gorlatov, Gaithersburg, Md., and Ling Huang, Gaithersburg, Md. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to molecules, particularly polypeptides, more particularly immunoglobulins (e.g., antibodies), comprising a variant Fc region, wherein said variant Fc region comprises at least one amino acid modification relative to a wild-type Fc region, which variant Fc region binds Fc.gamma.RIIIA and/or Fc.gamma.RIIA with a greater affinity, relative to a comparable molecule comprising the wild-type Fc region. The molecules of the invention are particularly useful in preventing, treating, or ameliorating one or more symptoms associated with a disease, disorder, or infection. The molecules of the invention are particularly useful for the treatment or prevention of a disease or disorder where an enhanced efficacy of effector cell function (e.g., ADCC) mediated by Fc.gamma.R is desired, e.g., cancer, infectious disease, and in enhancing the therapeutic efficacy of therapeutic antibodies the effect of which is mediated by ADCC." The patent application was filed on June 10, 2011 (13/158,169). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=84,45,645.PN.&OS=PN/84,45,645&RS=PN/84,45,645 Written by Amal Ahmed; edited by Jaya Anand. *** Weyerhaeuser N.R. Assigned Patent ALEXANDRIA, Va., May 24 -- Weyerhaeuser N.R., Federal Way, Wash., has been assigned a patent (8,445,563) developed by Jack G. Winterowd, Puyallup, Wash., Cheng Zhang, Rockville, Md., and Amar N. Neogi, Kenmore, Wash., for an "utilization of kraft lignin in phenol/formaldehyde bonding resins for OSB." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A resin for OSB comprising an aqueous resole reaction product of phenol, formaldehyde, alkaline metal hydroxide or carbonate, urea and a degraded lignin polymer having 35-65% solids, a pH of 8-13 and a viscosity 50-1000 centipoises. The phenol and formaldehyde are present in a molar ratio of 1.5 to 3.4 moles formaldehyde to 1 mole phenol and are 40 to 85% of the total solids added to the mixture. In one embodiment they are 50 to 75% of the total solids added to the mixture. The alkaline metal hydroxide or carbonate are 5 to 20% of the total solids added to the mixture. Urea is 5 to 35% of the total solids added to the mixture. The degraded lignin is 5 to 20% of the total solids added to the mixture. A method for making the resin and a product using the resin." The patent application was filed on Nov. 16, 2010 (12/947,703). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=84,45,563.PN.&OS=PN/84,45,563&RS=PN/84,45,563 Written by Amal Ahmed; edited by Jaya Anand. *** Johns Hopkins University Assigned Patent ALEXANDRIA, Va., May 24 -- Johns Hopkins University, Baltimore, has been assigned a patent (8,445,660) developed by Thomas August, Baltimore, and Ernesto Marques Jr., Baltimore, for chimeric vaccines. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient." The patent application was filed on June 28, 2010 (12/824,835). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=84,45,660.PN.&OS=PN/84,45,660&RS=PN/84,45,660 Written by Amal Ahmed; edited by Jaya Anand. *** STC.UNM Assigned Patent ALEXANDRIA, Va., May 24 -- STC.UNM, Albuquerque, N.M., has been assigned a patent (8,445,537) developed by six co-inventors for "compounds that inhibit human DNA ligases and methods of treating cancer." The co-inventors are Alan E. Tomkinson, Glenwood, Md., Xi Chen, Baltimore, Barbara Dziegielewska, Baltimore, Alexander D. Mackerell, Baltimore, Shijun Zhong, Ellicott City, Md., and Gerald M. Wilson, Middle River, Md. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases." The patent application was filed on Oct. 9, 2009 (12/576,410). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=84,45,537.PN.&OS=PN/84,45,537&RS=PN/84,45,537 Written by Amal Ahmed; edited by Jaya Anand. *** Black & Decker Inc. Assigned Patent ALEXANDRIA, Va., May 24 -- Black & Decker Inc., Newark, Del., has been assigned a patent (8,446,120) developed by Michael K. Forster, White Hall, Md., Matthew Velderman, Baltimore, and John C. Vanko, Timonium, Md., for an "electronic switching module for a power tool." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A power tool includes a tool housing, an electric motor inside the housing, and a power interface facilitating a connection to a power source. At least four actively-controlled power components are configured as an H-bridge to modulate a supply of power from the power interface to the electric motor. A user-actuated input unit outputs a first signal indicative of a desired power output level to the electric motor and a second signal indicative of a desired direction of current flow to the electric motor. A control unit controls the supply of power to the electric motor using two of said power components with synchronous rectification for pulse-width modulation (PWM) of the supply of power based on the first signal, and to control the direction of current flow to the electric motor using the other two of said power components based on the second signal." The patent application was filed on May 21, 2012 (13/476,634). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,446,120.PN.&OS=PN/8,446,120&RS=PN/8,446,120 Written by Kusum Sangma; edited by Anand Kumar. *** Rockwell Collins Assigned Patent ALEXANDRIA, Va., May 24 -- Rockwell Collins, Cedar Rapids, Iowa, has been assigned a patent (8,446,305) developed by four co-inventors for a "photonic analog to digital conversion." The co-inventors are Raymond Zanoni, Columbia, Md., Alistair J. Price, Ellicott City, Md., Peter J. Morgan, Glenelg, Md., and Phillip R. Koenig, Martelle, Iowa. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A photonic analog to digital converter includes one or more modulators configured to receive a first optical signal and a radio frequency signal. The one or more modulators is configured to modulate the first optical signal based on the radio frequency signal. The converter also includes circuitry configured to independently quantize one or more of phase, quadrature, and amplitude coordinates of the modulated signal. The circuitry provides the quantized coordinates to one or more electronic analog to digital converters." The patent application was filed on Sept. 30, 2009 (12/571,232). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,446,305&OS=8,446,305&RS=8,446,305 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Wyeth Assigned Patent ALEXANDRIA, Va., May 24 -- Wyeth, Madison, N.Y., has been assigned a patent (8,445,496) developed by four co-inventors for "crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-pipera- zinyl)propoxy]-3-quinolinecarbonitrile and methods of preparing the same." The co-inventors are Marc Sadler Tesconi, Monroe, N.Y., Gregg Feigelson, Chester, N.Y., Henry Strong, Somerset, N.J., and Hong Wen, North Potomac, Md. The abstract of the patent published by the U.S. Patent and Trademark Office states: "This invention is directed to a crystalline 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-pipera- zinyl)propoxy]-3-quinolinecarbonitrile monohydrate having an x-ray diffraction pattern wherein 2.theta. angles (.degree.) of significant peaks are at about: 9.19, 11.48, 14.32, 19.16, 19.45, 20.46, 21.29, 22.33, 23.96, 24.95, 25.29, 25.84, 26.55, 27.61, and 29.51, and a transition temperature of about 109.degree. C. to about 115.degree. C." The patent application was filed on June 22, 2010 (12/820,306). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=84,45,496.PN.&OS=PN/84,45,496&RS=PN/84,45,496 Written by Amal Ahmed; edited by Jaya Anand. *** EPA Assigned Patent ALEXANDRIA, Va., May 24 -- The U.S. Environmental Protection Agency has been assigned a patent (8,445,850) developed by four co-inventors for an "optical remote sensing of fugitive releases." The co-inventors are Eben Daniel Thoma, Cary, N.C., Cary Doman Secrest, Bethesda, Md., William A. Mitchell, New Hill, N.C., and William C. Squier, Angier, N.C. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Disclosed is an open-path optical sensor. Typically, the optical sensor directs UV radiation from a source assembly to a detector assembly along a monitoring path. The source assembly emits UV radiation corresponding to a signal channel and to a reference channel. The detector assembly detects UV radiation corresponding to the signal channel and to the reference channel. The detector assembly is in communication with a data acquisition system, which compares the intensity of the detected UV radiation corresponding to the signal channel to the intensity of the UV radiation corresponding to the reference channel." The patent application was filed on June 20, 2011 (13/164,046). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,445,850&OS=8,445,850&RS=8,445,850 Written by Arpi Sharma; edited by Anand Kumar. For more information about Targeted News Service products and services, please contact: Myron Struck, editor, Targeted News Service LLC, Springfield, Va., 703/304-1897; [email protected]; http://targetednews.com. -1126096 (c) 2013 Targeted News Service |