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U.S. Patents Awarded to Inventors in Pennsylvania (Dec. 29)
[December 29, 2012]

U.S. Patents Awarded to Inventors in Pennsylvania (Dec. 29)

(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Dec. 29 -- The following federal patents were awarded to inventors in Pennsylvania.

*** Merck Sharp & Dohme Assigned Patent for Hexahydrocyclopentyl[F]Indazole Carboxamides and Derivatives Thereof as Selective Glucocorticoid Receptor Modulators ALEXANDRIA, Va., Dec. 29 -- Merck Sharp & Dohme, Rahway, N.J., has been assigned a patent (8,338,472) developed by four co-inventors for "hexahydrocyclopentyl[F]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor modulators." The co-inventors are William P. Dankulich, Collegeville, Pa., Danielle M. McMaster, Boothwyn, Pa., Robert S. Meissner, Schwenksville, Pa., and Helen J. Mitchell, Richboro, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention is directed to hexahydrocyclopentylf]imidazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included." The patent application was filed on Feb. 16, 2009 (12/919,049). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,472&OS=8,338,472&RS=8,338,472 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Teva Women's Health Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Teva Women's Health, Woodcliff Lake, N.J., has been assigned a patent (8,338,396) developed by Robert G. Bell, Palm Harbor, Fla., Carole Ben-Maimon, Merion, Pa., and Beata Iskold, Livingston, N.J., for "oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology." The abstract of the patent published by the U.S. Patent and Trademark Office states: "This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressant and a kit containing the same." The patent application was filed on May 24, 2010 (12/786,283). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,396&OS=8,338,396&RS=8,338,396 Written by Satyaban Rath; edited by Hemanta Panigrahi.


*** Wyeth LLC Assigned Patent for Cut-point in PTEN Protein Expression that Accurately Identifies Tumors and is Predictive of Drug Response to a Pan-ErbB Inhibitor ALEXANDRIA, Va., Dec. 29 -- Wyeth LLC, Madison, N.J., has been assigned a patent (8,338,456) developed by six co-inventors for "cut-point in PTEN protein expression that accurately identifies tumors and is predictive of drug response to a pan-ErbB inhibitor." The co-inventors are Christina Marie Coughlin, Berwyn, Pa., Jay Marshall Feingold, Wynnewood, Pa., Daniel Stephen Johnston, Trappe, Pa., Anna Berkenblit, Needham, Mass., Andrew Louis Strahs, Maynard, Mass., and Charles Michael Zacharchuk, Westford, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value." The patent application was filed on Jan. 4, 2011 (12/984,043). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,456&OS=8,338,456&RS=8,338,456 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Merck Sharp & Dohme Assigned Patent for Isoquinolinone Potassium Channel Inhibitors ALEXANDRIA, Va., Dec. 29 -- Merck Sharp & Dohme, Rahway, N.J., has been assigned a patent (8,338,449) developed by six co-inventors for "isoquinolinone potassium channel inhibitors." The co-inventors are B. Wesley Trotter, Glenside, Pa., Christopher Claiborne, Cambridge, Mass., Gerald S. Ponticello, Lansdale, N.J., Charles J. McIntyre, Lansdale, Pa., Nigel Liverton, Harleysville, Pa., and David A. Claremon, Maple Glen, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to compounds having the structure ##STR00001## useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like." The patent application was filed on April 2, 2010 (12/753,572). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,449&OS=8,338,449&RS=8,338,449 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Wistar Institute, North Carolina State University Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Wistar Institute, Philadelphia, and North Carolina State University, Raleigh, N.C., have been assigned a patent (8,338,392) developed by Qihong Huang, Philadelphia, Alexander Deiters, Raleigh, N.C., and Kiranmai Gumireddy, Philadelphia, for "MicroRNA modulators and method for identifying and using the same." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention is a method for identifying agents which modulate microRNA activity. The invention involves contacting a cell harboring a microRNA and a microRNA binding sequence, which is operably linked to a nucleic acid molecule encoding a reporter protein, with a test agent increases or decreases the expression of the reporter protein thereby identifying a microRNA modulator. Antagonists identified by this screening assay are provided, as are methods for using the same to inhibit microRNA activity and prevent or treat disease." The patent application was filed on Feb. 20, 2009 (12/918,183). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,392&OS=8,338,392&RS=8,338,392 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** GlaxoSmithKline Assigned Patent ALEXANDRIA, Va., Dec. 29 -- GlaxoSmithKline, Philadelphia, has been assigned a patent (8,338,434) developed by Mark Andrew Seefeld, Collegeville, Pa., and Meagan B. Rouse, Collegeville, Pa., for "inhibitors of Akt activity." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Invented are novel pyrazole compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis." The patent application was filed on March 28, 2008 (12/593,415). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,434&OS=8,338,434&RS=8,338,434 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Johnson & Johnson Consumer Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Johnson & Johnson Consumer, Skillman, N.J., has been assigned a patent (8,338,348) developed by five co-inventors for "skin cleansing compositions with polyglycerol esters and hydrophobically modified polymers." The co-inventors are Emmanuel Anim-Danso, Cuyahoga Falls, Ohio, Lisa Gandolfi, Franklin Park, N.J., Euen Thomas Gunn, Trenton, N.J., Russel M. Walters, Philadelphia, and Michael J. Fevola, Belle Mead, N.J.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The methods and compositions of this invention relate to compositions containing polyglyceryl esters of fatty acids, low molecular weight hydrophobically-modified polymers and anionic and/or amphoteric surfactants having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin." The patent application was filed on Dec. 21, 2010 (12/974,188). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,348&OS=8,338,348&RS=8,338,348 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Avantor Performance Materials Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Avantor Performance Materials, Phillipsburg, N.J., has been assigned a patent (8,338,350) developed by Seiji Inaoka, Nazareth, Pa., for a "gluconic acid containing photoresist cleaning composition for multi-metal device processing." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A microelectronic photoresist cleaning composition suitable for cleaning multi-metal microelectronic devices and to do so without any substantial or significant galvanic corrosion occurring when there is a subsequent rinsing step employing water." The patent application was filed on Oct. 22, 2009 (12/998,499). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,350&OS=8,338,350&RS=8,338,350 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Arkema Assigned Patent for Hard Surface Cleaner Containing Polysulfonic Acid ALEXANDRIA, Va., Dec. 29 -- Arkema, King of Prussia, Pa., has been assigned a patent (8,338,353) developed by Nicholas M. Martyak, Doylestown, Pa., and Gary E. Stringer, Birdsboro, Pa., for a "hard surface cleaner containing polysulfonic acid." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention is directed toward improved aqueous hard surface cleaning compositions which include one or more polysulfonic acids The inclusion of one or more polysulfonic acids in a hard surface composition provides for improved removal of insoluble salt deposits resulting from hard water In an embodiment, the invention utilizes a foaming agent fragrance and a thickening agent." The patent application was filed on July 24, 2008 (12/667,589). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,353&OS=8,338,353&RS=8,338,353 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Centocor Ortho Biotech Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Centocor Ortho Biotech, Horsham, Pa., has been assigned a patent (8,338,171) developed by Bethany Swencki-Underwood, Radnor, Pa., and Michael Naso, Radnor, Pa., for a "baboon homolog of human CD147." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Polynucleotide sequences encoding a baboon homolog of human CD147 and polypeptides obtainable form the polynucleotides and uses are disclosed." The patent application was filed on Aug. 12, 2010 (12/855,214). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,338,171&OS=8,338,171&RS=8,338,171 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Becton, Dickinson and Co. Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Becton, Dickinson and Co., Franklin Lakes, N.J., has been assigned a patent (8,337,423) developed by Jason Mondro, Sparta, N.J., David R. Schiff, Highland Park, N.J., and Jonathan D. Albert, Philadelphia, for blood glucose sensor.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention is directed to an apparatus and method for blood sample acquisition and testing. The apparatus incorporates a test strip having a blood sample volume detection area in which a blood sample is accumulated and a minimum blood sample volume is detected. Once a minimum blood sample volume is detected, the test strip is moved with respect to the blood sample extraction site so that a bending surface of the test strip is presented to the blood sample, utilizing the surface tension of the blood sample droplet to facilitate movement of the blood sample to a measurement site on the strip where blood glucose in the sample is measured." The patent application was filed on July 14, 2009 (12/502,594). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,337,423&OS=8,337,423&RS=8,337,423 Written by Neha Bharti; edited by Jaya Anand.

*** Lutron Electronics Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Lutron Electronics, Coopersburg, Pa., has been assigned a patent (8,339,048) developed by six co-inventors for a hybrid light source. The co-inventors are Robert C. Newman Jr., Emmaus, Pa., Keith Joseph Corrigan, Allentown, Pa., Aaron Dobbins, Hopedale, Mass., Mehmet Ozbek, Allentown, Pa., Mark S. Taipale, Harleysville, Pa., and Joel S. Spira, Coopersburg, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A hybrid light source comprises a discrete-spectrum lamp (for example, a fluorescent lamp) and a continuous-spectrum lamp (for example, a halogen lamp). A control circuit individually controls the amount of power delivered to the discrete-spectrum lamp and the continuous-spectrum lamp in response to a phase-controlled voltage generated by a connected dimmer switch, such that a total light output of the hybrid light source ranges throughout a dimming range. The discrete-spectrum lamp is turned off and the continuous-spectrum lamp produces all of the total light intensity of the hybrid light source when the total light intensity is below a transition intensity. The continuous-spectrum lamp is driven by a continuous-spectrum lamp drive circuit, which is operable to conduct a charging current of a power supply of the dimmer switch and to provide a path for enough current to flow through the hybrid light source, such that the magnitude of the current exceeds rated latching and holding currents of a thyristor of the dimmer." The patent application was filed on Feb. 12, 2010 (12/704,781). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,339,048&OS=8,339,048&RS=8,339,048 Written by Arpi Sharma; edited by Anand Kumar.

*** Silberline Manufacturing Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Silberline Manufacturing, Tamaqua, Pa., has been assigned a patent (8,337,609) developed by five co-inventors for a "black pearlescent pigment with a metal layer." The co-inventors are Shufang Yu, Orefield, Pa., Peter Llyod Redmond, New Ringgold, Pa., Hai Hui Lin, Naperville, Ill., Chang Xu, Macungie, Pa., and Parfait Jean Marie Likibi, Mount Pleasant, S.C.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A pearlescent effect pigment having an opaque, dark or black color is disclosed. The black pearlescent pigment includes a platelet-shaped non-metal substrate, optionally an oxide layer, a template layer, and a metal layer. The pearlescent luster of the disclosed effect pigment is comparable to those of pure pearlescent effects. The disclosed method provides a cost-effective approach for the manufacturing of the disclosed effect pigment." The patent application was filed on Dec. 1, 2009 (12/628,779). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,37,609.PN.&OS=PN/83,37,609&RS=PN/83,37,609 Written by Amal Ahmed; edited by Jaya Anand.

*** Synthes USA Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Synthes USA, West Chester, Pa., has been assigned a patent (8,337,500) developed by five co-inventors for a "drilling/milling guide and keel cut preparation system." The co-inventors are Rudolph Bertagnoli, Straubing, Germany, Daniel Murrey, Charlotte, N.C., John P. Furda, Hamilton, N.J., Marc Reichen, West Chester, Pa., and David Gerber, West Chester, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "An instrument system, associated milling or drilling guide and method include use of a trial implant of a size corresponding to an actual implant for the intervertebral space, with a milling guide mounted on the trial implant. The milling guide includes a longitudinal guide chamber which is tapered from a forward end to a rearward end. The system also includes a cutting tool which is received in the guide chamber in order to form a cutout in an adjacent vertebra. This cutting tool includes a bearing member which pivotally engages the rearward end to form a pivot axis for the cutting tool in the tapered guide chamber. Either the milling guide can be inverted to form the cutout in the other vertebra; or the milling guide can be provided with two guide chambers, to be used with one cutting tool moved between them or two respective cutting tools." The patent application was filed on July 30, 2007 (12/375,710). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,37,500.PN.&OS=PN/83,37,500&RS=PN/83,37,500 Written by Amal Ahmed; edited by Jaya Anand.

*** Globus Medical Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Globus Medical, Audubon, Pa., has been assigned a patent (8,337,559) developed by eight co-inventors for an expandable vertebral prosthesis. The co-inventors are Noah Hansell, King of Prussia, Pa., William S. Rhoda, Drexel Hill, Pa., Andrew Lee, Oreland, Pa., Michael L. Boyer II, Paoli, Pa., Paul W. Millhouse, Philadelphia, Edward Karpowicz, Swedesboro, N.J., Matthew Hansell, Schwenksville, Pa., and Craig Billman, Phoenixville, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to an expandable prosthetic implant device for engagement between vertebrae generally comprising an inner member, outer member, and gear member positioned coaxial with respect to each other such that the inner and outer members are moveable relative to each other along an axis. The gear member is axially fixed to the outer member and freely rotatable with respect to the outer member and the gear member threadedly engages a threaded portion of the inner member to translate inner member along the axis. The implant is configured to engage the vertebrae in a predetermined alignment and the gear member includes gear teeth exposed to the exterior and configured to be accessible by a tool member at a plurality of angular positions around the perimeter of the implant device." The patent application was filed on June 1, 2010 (12/791,623). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,37,559.PN.&OS=PN/83,37,559&RS=PN/83,37,559 Written by Amal Ahmed; edited by Jaya Anand.

*** Medrad Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Medrad, Indianola, Pa., has been assigned a patent (8,337,456) developed by five co-inventors for a "syringe having a proximal end with an outward extending lip." The co-inventors are Ralph E. Schriver, Tarentum, Pa., Michael A. Spohn, Butler, Pa., Thomas P. Joyce, Wilkins Township, Pa., Herbert M. Grubic, Pittsburgh, and John A. Haury, Sewickly, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A syringe includes a body having a distal end, a proximal end and a center section therebetween, a plunger movably disposed in the body, and a hollow alignment flange for orienting and manipulating the syringe." The patent application was filed on May 7, 2009 (12/437,011). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,37,456.PN.&OS=PN/83,37,456&RS=PN/83,37,456 Written by Amal Ahmed; edited by Jaya Anand.

*** E.I. du Pont de Nemours Assigned Patent ALEXANDRIA, Va., Dec. 29 -- E.I. du Pont de Nemours, Wilmington, Del., has been assigned a patent (8,338,152) developed by Howard Glenn Damude, Hockessin, Del., and Quinn Qun Zhu, West Chester, Pa., for a "delta-8 desaturases and their use in making polyunsaturated fatty acids." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding delta-8 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) and using these delta-8 desaturases in plants." The patent application was filed on April 18, 2012 (13/449,395). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,338,152.PN.&OS=PN/8,338,152&RS=PN/8,338,152 Written by Kusum Sangma; edited by Anand Kumar.

*** University of Pennsylvania Assigned Patent ALEXANDRIA, Va., Dec. 29 -- The University of Pennsylvania, Philadelphia, has been assigned a patent (8,338,111) developed by four co-inventors for an endometriosis markers. The co-inventors are Kurt T. Barnhart, Bryn Mawr, Pa., Beata Seeber, Ardmore, Pa., George L. Gerton, Bryn Mawr, Pa., and Mary D. Sammel, Wallingford, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to methods for determining a risk or identifying a condition associated with the presence of endometriosis in a subject as well as testing a candidate compound for a therapeutic activity for the treatment of endometriosis and sorting patients based on the risk of having endometriosis. Specifically, the methods utilize novel markers for assessing the risk of the patient having endometriosis." The patent application was filed on April 26, 2011 (13/094,660). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,338,111.PN.&OS=PN/8,338,111&RS=PN/8,338,111 Written by Kusum Sangma; edited by Anand Kumar.

*** Immunomedics Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Immunomedics, Morris Plains, N.J., has been assigned a patent (8,338,140) developed by four co-inventors for a "polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites." The co-inventors are Serengulam V. Govindan, Summit, N.J., Sung-Ju Moon, New Providence, N.J., David M. Goldenberg, Mendham, N.J., and Chien-Hsing Chang, Downingtown, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention concerns methods and compositions for delivery of therapeutic agents to target cells, tissues or organisms. In preferred embodiments, the therapeutic agents are delivered in the form of therapeutic-loaded polymers that may comprise many copies of one or more therapeutic agents. In more preferred embodiments, the polymer may be conjugated to a peptide moiety that contains one or more haptens, such as HSG. The agent-polymer-peptide complex may be delivered to target cells by, for example, a pre-targeting technique utilizing bispecific or multispecific antibodies or fragments, having at least one binding arm that recognizes the hapten and at least a second binding arm that binds specifically to a disease or pathogen associated antigen, such as a tumor associated antigen. Methods for synthesizing and using such therapeutic-loaded polymers and their conjugates are provided." The patent application was filed on Sept. 27, 2011 (13/246,389). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,338,140.PN.&OS=PN/8,338,140&RS=PN/8,338,140 Written by Kusum Sangma; edited by Anand Kumar.

*** Microchip Technology Assigned Patent ALEXANDRIA, Va., Dec. 29 -- Microchip Technology, Chandler, Ariz., has been assigned a patent (8,339,113) developed by Scott Dearborn, Brackney, Pa., for a "buck switch-mode power converter large signal transient response optimizer." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A switch mode power supply (SMPS) response to a disturbance is improved by using a hysteretic control in combination with a fixed frequency, pulse-width modulated (PWM) controller for providing robust control and optimizing the response to disturbances in buck or buck derived switch mode power supply (SMPS) system topologies." The patent application was filed on July 19, 2010 (12/839,012). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,339,113.PN.&OS=PN/8,339,113&RS=PN/8,339,113 Written by Kusum Sangma; edited by Anand Kumar.

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