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U.S. Patents Awarded to Inventors in Massachusetts (Nov. 9)(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Nov. 9 -- The following federal patents were awarded to inventors in Massachusetts. *** Teradyne Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Teradyne, North Reading, Mass., has been assigned a patent (8,305,751) developed by Brian S. Merrow, Harvard, Mass., for "vibration isolation within disk drive testing systems." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A disk drive test slot includes a housing that defines a test compartment for receiving and supporting a disk drive transporter carrying a disk drive for testing. The housing also defines an open end that provides access to the test compartment for insertion and removal of disk drive transporter carrying a disk drive for testing. The disk drive test slot also includes a mounting plate connected to the housing. One or more isolators are disposed between the housing and the mounting plate. The one or more isolators are operable to inhibit transmission of vibrational energy between the housing and the mounting plate." The patent application was filed on April 17, 2008 (12/105,105). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,751&OS=8,305,751&RS=8,305,751 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Casa Systems Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Casa Systems, Andover, Mass., has been assigned a patent (8,306,166) developed by David Fox, Bolton, Mass., for a "system and method for detecting burst noise during quadrature amplitude modulation communications." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A system and method for detecting burst noise during quadrature amplitude modulation (QAM) communications are provided. A QAM signal is acquired at a receiver in communication with a network. The QAM signal is demodulated at the receiver to identify a plurality of symbols. Amplitudes for each of the plurality of symbols are determined, and are compared to a predetermined threshold. For each amplitude that is greater than the predetermined threshold, information is recorded at the receiver relating to a burst noise event. The magnitude of the burst noise can be determined by measuring a difference between a received constellation point and a perimeter constellation point closest to the received constellation point. The information about the burst noise event can be transmitted to an error correction module for reducing future burst noise in the network. Equalizer coefficients and tracking loop performance can be adjusted/enhanced using the burst noise information." The patent application was filed on Jan. 17, 2012 (13/351,699). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,306,166&OS=8,306,166&RS=8,306,166 Written by Arpi Sharma; edited by Anand Kumar. *** Vertex Pharmaceutical Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Vertex Pharmaceutical, Cambridge, Mass., has been assigned a patent (8,304,423) developed by Robert J. Davies, Watertown, Mass., and Jinwang Xu, Framingham, Mass., for "modulators of muscarinic receptors." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases." The patent application was filed on June 29, 2011 (13/171,652). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,304,423&OS=8,304,423&RS=8,304,423 Written by Neha Bharti; edited by Jaya Anand. *** Affymetrix Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Affymetrix, Santa Clara, Calif., has been assigned a patent (8,305,565) developed by Akim F. Lennhoff, Cambridge, Mass., and Nathan K. Weiner, Upton, Mass., for a "system, method, and product for multiple wavelength detection using single source excitation." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An embodiment of a method for adjusting system gain of a biological probe array scanner for a plurality of fluorophore species is described that comprises setting an excitation beam comprising an excitation wavelength at a first power level that elicits an optimal signal to noise ratio response from a first fluorophore species; scanning a biological probe array with the excitation beam; setting the excitation beam comprising the excitation wavelength at a second power level different than the first power level that elicits the optimal signal to noise ratio response from a second fluorophore species; and scanning the biological probe array with the excitation beam." The patent application was filed on Feb. 1, 2010 (12/697,910). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,565&OS=8,305,565&RS=8,305,565 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Zink Imaging Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Zink Imaging, Bedford, Mass., has been assigned a patent (8,305,408) developed by four co-inventors for a "nonrotating platen for thermal printing." The co-inventors are Kenneth J. Launie, Cambridge, Mass., Leo R. Lechtenberg, Middleboro, Mass., Juan C. Van Dijk, Sudbury, Mass., and William T. Vetterling, Lexington, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Devices and methods for thermally printing on a thermal image member are disclosed using a thermal print head and a nonrotating platen. The nonrotating platen is adapted to bias the thermal imaging member against the print head. The nonrotating platen includes an elastic member and a mounting means for securing at least one end of the elastic member with respect to the print head. A portion of the thermal imaging member is placed in a printing nip formed between a thermal print head and the nonrotating platen. The print head exerts a torque on the elastic member when the elastic member biases the imaging member against the print head. The thermal imaging member is translated along a transport direction through the printing nip, such that at least one surface of the imaging member slides across the nonrotating platen. The print head forms an image upon the translated thermal imaging member." The patent application was filed on May 25, 2007 (11/753,753). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,408&OS=8,305,408&RS=8,305,408 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Massachusetts Institute of Technology Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Massachusetts Institute of Technology, Cambridge, Mass., has been assigned a patent (8,305,050) developed by Yogesh Ramadass, Cambridge, Mass., and Anantha Chandrakasan, Belmont, Mass., for a "circuit and method to startup from very low voltages and improve energy harvesting efficiency in thermoelectric harvesters." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An energy harvesting system is provided that includes a startup module for starting the energy harvesting system operation from a completely OFF state. The startup module uses mechanical vibrations due to motion to trigger a switch which permits the startup module to charge one or more first capacitive elements so to as reach a first defined voltage. A storage module buffers energy obtained from a thermoelectric harvester to be used by a load device. The storage module commences storing energy from the thermoelectric harvester when the first defined voltage has been reached allowing charging of one or more second capacitive elements to reach a second defined voltage. A DC-DC converter module provides regulated voltage to the load device after energy has been transferred from the thermoelectric harvester. The DC-DC converter module determines whether the second defined voltage has been reached and releases stored energy in the one or more first capacitive elements and the load device." The patent application was filed on Oct. 12, 2009 (12/577,421). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,305,050.PN.&OS=PN/8,305,050&RS=PN/8,305,050 Written by Kusum Sangma; edited by Anand Kumar. *** ArQule Assigned Patent ALEXANDRIA, Va., Nov. 9 -- ArQule, Woburn, Mass., has been assigned a patent (8,304,425) developed by six co-inventors for "pyrrolidinone, pyrrolidine-2,5-dione, pyrrolidine and thiosuccinimide derivatives, compositions and methods for treatment of cancer." The co-inventors are Jianqiang Wang, Acton, Mass., Syed M. Ali, North Andover, Mass., Eugene Kelleher, Wellesley, Mass., Yanbin Liu, Acton, Mass., Jason Hill, Auburndale, Mass., and Mark A. Ashwell, Carlisle, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention. ##STR00001##." The patent application was filed on June 19, 2008 (12/664,550). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,304,425&OS=8,304,425&RS=8,304,425 Written by Neha Bharti; edited by Jaya Anand. *** Infinity Discovery Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Infinity Discovery, Cambridge, Mass., has been assigned a patent (8,304,428) developed by seven co-inventors for "compounds and methods for inhibiting the interaction of BCL proteins with binding partners." The co-inventors are Alfredo C. Castro, Winchester, Mass., Michael J. Grogan, Winchester, Mass., Edward B. Holson, Newton Highlands, Mass., Brian T. Hopkins, Newton, Mass., Nii O. Koney, New York, Stephane Peluso, Somerville, Mass., and Daniel A. Snyder, Somerville, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer." The patent application was filed on April 2, 2010 (12/753,319). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,304,428&OS=8,304,428&RS=8,304,428 Written by Neha Bharti; edited by Jaya Anand. *** VidSys Assigned Patent ALEXANDRIA, Va., Nov. 9 -- VidSys, Vienna, Va., has been assigned a patent (8,305,211) developed by Stephen Jeffrey Morris, Harvard, Mass., and Steven Arnold Bolton, Harvard, Mass., for a "method and apparatus for surveillance system peering." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A security installation positions a peering ability with a peer installation by establishing a peering agreement to define the conditions constituting a situation for which peering applies, and identifies the resources and assets which will be shared, as well as the duration of the peering, typically until the resolution of the exigent situation or circumstances that prompted the peering. Peering selectively couples security installations for monitoring a particular upon determining that a situation responsive to mediation has occurred within an area monitored by the security installation for monitoring an area. The security installation initiates a peering invitation to a peer installation, in which the peer installation is configured to share resources with the security installation for mitigating the cause of the situation. The resulting peered access provides communication between the peer installation and the security installation, the access being temporary and conditional on the exigency of the determined situation." The patent application was filed on Oct. 1, 2009 (12/571,953). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,305,211.PN.&OS=PN/8,305,211&RS=PN/8,305,211 Written by Kusum Sangma; edited by Anand Kumar. *** Dassault Systemes SolidWorks Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Dassault Systemes SolidWorks, Waltham, Mass., has been assigned a patent (8,305,376) developed by Ruijiang Ran, Westford, Mass., Chun-Yi Hu, Lexington, Mass., and Hailong Li, Acton, Mass., for a "locally updating a three-dimensional model." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Updating a three-dimensional model includes generating a three-dimensional model comprised of components, modifying one of the components, determining other components having a possible changing effect on the three-dimensional model as a result of modifying the one component, and constructing a modified version of the three-dimensional model by regenerating the modified component and the other components having the possible changing effect while not regenerating remaining ones of the components not having the possible changing effect. The modified version achieves the same result as revising the three-dimensional model by regenerating each one of components." The patent application was filed on April 12, 2007 (11/734,688). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,376&OS=8,305,376&RS=8,305,376 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Maxim Integrated Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Maxim Integrated, San Jose, Calif., has been assigned a patent (8,305,131) developed by Hae-Seung Lee, Bedford, Mass., for a "passive offset and overshoot cancellation for sampled-data circuits." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A zero-crossing detector with effective offset cancellation includes a set of series connected capacitors and an amplifier having an input terminal. An offset capacitor is operatively connected between the amplifier and the set of series connected capacitors. A switch is operatively connected to the input terminal, and an offset sampling capacitor is operatively connected to the switch. The switch connects the offset sampling capacitor to the input terminal of the amplifier during a charge transfer phase." The patent application was filed on June 15, 2009 (12/484,469). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,305,131.PN.&OS=PN/8,305,131&RS=PN/8,305,131 Written by Kusum Sangma; edited by Anand Kumar. *** Spectral Sciences Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Spectral Sciences, Burlington, Mass., has been assigned a patent (8,305,575) developed by seven co-inventors for an "adaptive spectral sensor and methods using same." The co-inventors are Neil Goldstein, Belmont, Mass., Jason A. Cline, Burlington, Mass., Pajo Vujkovic-Cvijin, Burlington, Mass., Steven M. Adler-Golden, Newtonville, Mass., Marsha J. Fox, Lexington, Mass., Brian Gregor, Waltham, Mass., and Jamine Lee, Burlington, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "An adaptive spectral sensor, and methods of using the sensor. The sensor uses a programmable band pass transmission filter to produce both contrast signals, which discriminate specific target materials from background materials by comparing spectral signatures in hardware, and scene radiance spectra. The adaptive spectral sensor may measure one or more scene spectra and may form a spectral image. The sensor may automatically adjust to changing spectral, spatial and temporal conditions in the environment being monitored, by changing sensor resolution in those dimensions and by changing the detection band pass. The programmable band pass can be changed on-the-fly in real time to implement a variety of detection techniques in hardware or measure the spatial or spectral signatures of specific materials and scenes." The patent application was filed on June 23, 2009 (12/489,906). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,575&OS=8,305,575&RS=8,305,575 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** E Ink Assigned Patent for Dielectrophoretic Displays ALEXANDRIA, Va., Nov. 9 -- E Ink, Cambridge, Mass., has been assigned a patent (8,305,341) developed by Alexi C. Arango, Somerville, Mass., Joseph M. Jacobson, Newton Centre, Mass., and Karl R. Amundson, Cambridge, Mass., for dielectrophoretic displays. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A dielectrophoretic display comprises a substrate having walls defining at least one cavity, the cavity having a viewing surface and a side wall inclined to the viewing surface; a suspending fluid contained within the cavity; a plurality of at least one type of particle suspended within the suspending fluid; and means for applying to the fluid an electric field effective to cause dielectrophoretic movement of the particles to the side wall of the cavity." The patent application was filed on Aug. 28, 2009 (12/549,763). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,305,341&OS=8,305,341&RS=8,305,341 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** University of Massachusetts Assigned Patent ALEXANDRIA, Va., Nov. 9 -- The University of Massachusetts, Boston, has been assigned a patent (8,304,530) developed by four co-inventors for "methods and compositions for enhancing the efficacy and specificity of RNA silencing." The co-inventors are Phillip D. Zamore, Northboro, Mass., Gyorgy Hutvagner, Worcester, Mass., Dianne Schwarz, Westborough, Mass., and Martin Simard, Deschambault, Canada. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides methods of enhancing the efficacy and specificity of RNA silencing. The invention also provides compositions for mediating RNA silencing. In particular, the invention provides siRNAs, siRNA-like molecules, shRNAs, vectors and transgenes having improved specificity and efficacy in mediating silencing of a target gene. Therapeutic methods are also featured." The patent application was filed on March 23, 2010 (12/729,892). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,530.PN.&OS=PN/83,04,530&RS=PN/83,04,530 Written by Amal Ahmed; edited by Jaya Anand. *** Harvard College, Dana-Farber Cancer Institute Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Harvard College, Cambridge, Mass., and Dana-Farber Cancer Institute, Boston, have been assigned a patent (8,304,451) developed by Ralph Mazitschek, Arlington, Mass., Nicholas Paul Kwiatkowski, Auburn, Mass., and James Elliot Bradner, Cambridge, Mass., for "histone deacetylase and tubulin deacetylase inhibitors." The abstract of the patent published by the U.S. Patent and Trademark Office states: "In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel inhibitors of histone deacetylases, tubulin deacetylases, and/or aggresome inhibitors, and pharmaceutically acceptable salts and derivatives thereof. The inventive compounds fall into two classes--"isotubacin" class and "isoisotubacin" class--all of which include a 1,3-dioxane core. The present invention further provides methods for treating disorders regulated by histone deacetylase activity, tubulin deacetylase activity, and/or the aggresome (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, protein degradation disorders, protein deposition disorders, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention." The patent application was filed on May 2, 2007 (12/299,430). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,451.PN.&OS=PN/83,04,451&RS=PN/83,04,451 Written by Amal Ahmed; edited by Jaya Anand. *** Solutia Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Solutia, St. Louis, Mich., has been assigned a patent (8,304,516) developed by Pol D'Haene, Kessel-Lo, Belgium, Nandan Ukidwe, Worcester, Mass., and Paul Van Lierde, Haacht, Belgium, for a "continuous washing of poly(vinyl butyral)." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides a method for continuously washing poly(vinyl butyral) in which a poly(vinyl butyral) slurry is passed through multiple continuous stirred tank reactors, each of which is adjusted to specific processing parameters that allow for continuous input, washing, and removal of poly(vinyl butyral). The resulting poly(vinyl butyral) can then be dried to form a powder resin that can be used in place of conventional poly(vinyl butyral) resin. In an alternative embodiment, a counter current screw washing unit is provided that passes wash water over the poly(vinyl butyral) in a direction opposite to the flow of the poly(vinyl butyral), thereby allowing the continuous washing of the poly(vinyl butyral) resin." The patent application was filed on June 14, 2011 (13/160,089). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,516.PN.&OS=PN/83,04,516&RS=PN/83,04,516 Written by Amal Ahmed; edited by Jaya Anand. *** Genzyme Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Genzyme, Cambridge, Mass., has been assigned a patent (8,304,447) developed by fourteen co-inventors for "2-acylaminopropoanol-type glucosylceramide synthase inhibitors." The co-inventors are Craig Siegel, Woburn, Mass., Cecilia M. Bastos, South Grafton, Mass., David J. Harris, Lexington, Mass., Angeles Dios, Waltham, Mass., Edward Lee, Sudbury, Mass., Richard Silva, Needham, Mass., Lisa M. Cuff, Leominster, Mass., Mikaela Levine, Swampscott, Mass., Cassandra A. Celatka, Hull, Mass., Frederic Vinick, Lexington, Mass., Thomas H. Jozefiak, Belmont, Mass., Yibin Xiang, Acton, Mass., John Kane, Maynard, Mass., and Junkai Liao, Tewksbury, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A compound is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The subject has type 2 diabetes; renal hypertrophy or hyperplasia associated with diabetic nephropathy; Tay-Sachs; Gaucher's; or Fabry's disease. Methods of decreasing plasma TNF-.alpha., lowering blood glucose levels, decreasing glycated hemoglobin levels, inhibiting glucosylceramide synthase, and lowering glycosphingolipid concentrations in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. ##STR00001##." The patent application was filed on May 30, 2008 (12/601,871). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,447.PN.&OS=PN/83,04,447&RS=PN/83,04,447 Written by Amal Ahmed; edited by Jaya Anand. *** Catabasis Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Catabasis Pharmaceuticals, Cambridge, Mass., has been assigned a patent (8,304,552) developed by four co-inventors for "fatty acid niacin conjugates and their uses." The co-inventors are Jill C. Milne, Brookline, Mass., Michael R. Jirousek, Cambridge, Mass., Jean E. Bemis, Arlington, Mass., and Chi B. Vu, Arlington, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate." The patent application was filed on March 22, 2012 (13/427,001). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,552.PN.&OS=PN/83,04,552&RS=PN/83,04,552 Written by Amal Ahmed; edited by Jaya Anand. *** Paratek Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Paratek Pharmaceuticals, Boston, has been assigned a patent (8,304,445) developed by four co-inventors for "7-pyrazolyl tetracycline compounds and methods of use thereof." The co-inventors are Sophie Huss, Madrid, Spain, Jose M. Bueno, Madrid, Spain, Jose M. Fiandor, Madrid, Spain, and Roger Frechette, Reading, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides compounds of Formula (I) and related methods and formulations: ##STR00001## wherein: A represents a pyrazole ring optionally substituted by one or more R groups." The patent application was filed on March 1, 2011 (13/038,102). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,445.PN.&OS=PN/83,04,445&RS=PN/83,04,445 Written by Amal Ahmed; edited by Jaya Anand. *** Catabasis Pharmaceuticals Assigned Patent for Fatty Acid Niacin Conjugates and Their Uses ALEXANDRIA, Va., Nov. 9 -- Catabasis Pharmaceuticals, Cambridge, Mass., has been assigned a patent (8,304,551) developed by four co-inventors for "fatty acid niacin conjugates and their uses." The co-inventors are Jill C. Milne, Brookline, Mass., Michael R. Jirousek, Cambridge, Mass., Jean E. Bemis, Arlington, Mass., and Chi B. Vu, Arlington, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate." The patent application was filed on Aug. 31, 2010 (12/872,555). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,04,551.PN.&OS=PN/83,04,551&RS=PN/83,04,551 Written by Amal Ahmed; edited by Jaya Anand. *** Enanta Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Enanta Pharmaceuticals, Watertown, Mass., has been assigned a patent (8,304,385) developed by four co-inventors for "macrocyclic tetrazolyl hepatitis C serine protease inhibitors." The co-inventors are Ying Sun, Waltham, Mass., Dong Liu, Newton, Mass., Yat Sun Or, Watertown, Mass., and Zhe Wang, Hockessin, Del. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to compounds of Formula I, II, III or IV, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention." The patent application was filed on Nov. 14, 2008 (12/270,963). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,304,385&OS=8,304,385&RS=8,304,385 Written by Neha Bharti; edited by Jaya Anand. *** Coley Pharmaceutical Group, Coley Pharmaceutical, Pfizer Assigned Patent ALEXANDRIA, Va., Nov. 9 -- Coley Pharmaceutical Group, New York, Coley Pharmaceutical, Dusseldorf, Germany, and Pfizer, New York, have been assigned a patent (8,304,396) developed by seven co-inventors for immunostimulatory nucleic acids. The co-inventors are Arthur M. Krieg, Wellesley, Mass., Ulrike Samulowitz, Langenfeld, Germany, Jorg Vollmer, Dusseldorf, Germany, Eugen Uhlmann, Glashuetten, Germany, Marion Jurk, Dormagen, Germany, Grayson B. Lipford, Watertown, Mass., and Robert Rankin, Hemmen, the Netherlands. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to a class of soft or semi-soft CpG immunostimulatory oligonucleotides that are useful for stimulating an immune response." The patent application was filed on Oct. 4, 2006 (11/542,845). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,304,396&OS=8,304,396&RS=8,304,396 Written by Neha Bharti; edited by Jaya Anand. *** WiTricity Assigned Patent ALEXANDRIA, Va., Nov. 9 -- WiTricity, Watertown, Mass., has been assigned a patent (8,304,935) developed by seven co-inventors for a "wireless energy transfer using field shaping to reduce loss." The co-inventors are Aristeidis Karalis, Boston, Andre B. Kurs, Chestnut Hill, Mass., Andrew J. Campanella, Waltham, Mass., Konrad J. Kulikowski, Somerville, Mass., Katherine L. Hall, Westford, Mass., Marin Soljacic, Belmont, Mass., and Morris P. Kesler, Bedford, Mass. The abstract of the patent published by the U.S. Patent and Trademark Office states: "In embodiments of the present invention improved capabilities are described for a method and system comprising a source resonator optionally coupled to an energy source and a second resonator located a distance from the source resonator, where the source resonator and the second resonator are coupled to provide near-field wireless energy transfer among the source resonator and the second resonator and where the field of at least one of the source resonator and the second resonator is shaped to avoid a loss-inducing object." The patent application was filed on Dec. 28, 2009 (12/647,763). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,304,935.PN.&OS=PN/8,304,935&RS=PN/8,304,935 Written by Kusum Sangma; edited by Anand Kumar. For more information about Targeted News Service products and services, please contact: Myron Struck, editor, Targeted News Service LLC, Springfield, Va., 703/304-1897; [email protected]; http://targetednews.com. -1105078 (c) 2012 Targeted News Service |