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Darwin's 200th Birthday: Evolutionary Biology Experts Available
[January 29, 2009]

Darwin's 200th Birthday: Evolutionary Biology Experts Available


MADISON, Wis., Jan 29, 2009 (ASCRIBE NEWS via COMTEX) --
With Charles
Darwin's 200th birthday coming up in February, several
University of Wisconsin-Madison experts are available to
talk about the evolutionary biologist and related research.
Humans: Still evolving, only faster
When many people think about evolution, they may think
about ancient apes morphing into humans, or perhaps Darwin's
famous Galapagos finches. But modern humans are just as
subject to the pressures of natural selection and, in fact,
human evolution has accelerated during the past 5,000 years,
according to UW-Madison anthropologist John Hawks. Hawks
uses modern-day variation among human populations to
understand and reconstruct our evolutionary history. Though
people from around the world are genetically very similar,
with individuals differing by only around 0.1 percent of
their DNA, a handful of genes are very highly variable. The
present distribution of such genes provides a living record
of our evolutionary past.
Hawks is currently expanding his studies to the evolution
and spread of human languages and other cultural
"hitchhikers" that reflect the movements and influence of
ancient populations. The Bantu family of languages, for
example, is distributed across central Africa in a pattern
that matches well with the spread of farming. He is
investigating links between genetic changes and cultural
innovations throughout human evolutionary history. CONTACT:
John Hawks, 608-262-8726, [email protected]
Evolving germs
Perhaps the most relevant and observable forms of
evolution in action occur in the microorganisms that cause
disease. Tony Goldberg, a professor in the UW-Madison School
of Veterinary Medicine, studies the ecology and evolution of
disease and disease-causing organisms. Most famously,
disease-causing bacteria that survive antibiotic regimens
can evolve resistance to the drugs used to fight
infection. Viruses evolve to adapt to new hosts and
environments. The AIDS virus, for example, was not always
adapted to humans. The virus that infects humans today and
that sparked a global epidemic evolved from a simian virus
found in chimpanzees that was first transmitted to humans
through the bush meat trade in central Africa no later than
the 1930s. The virus's first human victim, explains
Goldberg, was probably infected through a wound exposed to
animal blood.
The challenge, according to Goldberg, is to discover what
other types of harmful microbes could enter the human
population in similar ways. Only by understanding how,
where and why humans and other species exchange pathogens
can such transmission be averted. Goldberg's research on
this topic spans several continents and disease systems,from bacteria
in Ugandan primates to West Nile virus in the
suburbs of Chicago. CONTACT: Tony Goldberg, 608-890-2618,
[email protected]
What's the trouble with intelligent design?
Intelligent design (ID) is embodied in the idea that some
of nature's adaptations - the vertebrate eye, for example -
are too complex to have evolved on their own and required
the intervention of an "intelligent designer": God. The
catch with ID, argues UW-Madison philosophy professor
Elliott Sober, is two-fold. First, it isn't true that
complex adaptations could not have evolved by natural
selection. Second, the ID hypothesis itself isn't
testable. In science, testing a hypothesis requires figuring
out what the hypothesis predicts. What features of the eye
does the ID hypothesis predict? Without information about
the goals and abilities that the designer has, this question
can't be answered, Sober explains. The ID hypothesis can
"accommodate" any observation, he says. "If you observe X,
you can construct the hypothesis that an intelligent
designer made X exist. But accommodating what we observe
isn't the same as predicting what we should observe."
Coping with evolution
There is no escaping that evolution is a pillar of modern
biology. And while some major religions can and do
accommodate the tenets of evolutionary science, how do
spiritually minded scientists and others integrate the ideas
of evolving life, geological time and the big questions of
cosmology into their spiritual worldviews? For UW-Madison
historian of science Lynn Nyhart, the pages of history offer
insight that can be especially valuable for students and
others wrestling with the apparent conflicts between
evolution and biblical interpretation. If you take
evolution as a fact, says Nyhart, what do you do about your
spiritual inclinations and needs?
The experiences of scientists in the first generations
after the publication of Darwin's "On the Origin of Species"
reveal a burst of spiritual creativity as they sought to
address this problem. Evolutionists seeking to maintain
their spiritual lives adopted new readings of the Bible,
looked to older traditions that relied less directly on the
Bible, discovered non-Western spiritual traditions, or found
new spiritual meaning in art, music, poetry, and philosophy.
Belief in the truth of evolution, Nyhart shows, has never
required scientists to abandon the spiritual realm. CONTACT:
Lynn Nyhart, 608-262-3492, [email protected]
The yeast we can do
Darwin may have gotten his evolutionary insight from
observing nature's stunning breadth of forms, but assistant
genetics professor Audrey Gasch finds hers inside the tiny
sphere of the yeast cell, whose basic, cellular physiology
closely resembles our own. A geneticist and biochemist by
training, Gasch had been studying the genetic and cellular
responses of yeast to environmental stress in the lab for
years, when the thought occurred to her: Perhaps her lab
strains were wimps compared to wild yeast - or, at least,
different.

Her research on wild cells taken from locations
worldwide, including Wisconsin soils, has now confirmed the
hunch. Wild yeast differ tremendously from lab strains - and
each other - in their ability to survive environmental
stresses, including freezing and thawing, and high
concentrations of ethanol, which they produce as they
ferment wine, beer and biofuels. She's now probing this
natural variation to understand how the traits of cells
evolve at the most basic level: that of genes. Her work has
implications for everything from cancer biology to biofuels
production. CONTACT: Audrey Gasch, 608-265-0859,
[email protected]
Through history's lens
Ronald Numbers, Hilldale Professor of the History of
Science and Medicine, is one of the world's leading
authorities on the collision of science and religion, from
Galileo to the recently opened creation museum in
Kentucky. The son of a Seventh-Day Adventist minister, he
grew up believing his church's literal reading of the Bible;
his studies in science eventually challenged those
beliefs. His publications include "The Creationists,"
Science and Christianity in Pulpit and Pew," "Galileo Goes
to Jail, and Other Myths About Science and Religion," and
"Darwinism Comes to America." Numbers can comment on the
mainstream responses to Darwinism, what Darwin really wrote
about in "On the Origin of Species" (there is only one
sentence on humans in the book), and what we usually get
wrong about Darwinism, natural selection and evolution. He
is sought by critics and believers alike for his expertise
and is in high demand in this anniversary year, including a
lecture at the Vatican in March. CONTACT: Ron Numbers,
608-262-3701, [email protected]
Detailing the origin of species
One hundred fifty years after Charles Darwin published
"On the Origin of Species," UW-Madison assistant professor
of genetics Bret Payseur is working to answer the same basic
question posed in that seminal work: How do new species
arise? While Darwin could only speculate about biological
mechanisms to explain the diversity he observed, Payseur is
tackling the question with an arsenal of modern molecular
tools to identify genetic barriers that can lead to the
evolution of new species.
He also studies genetic variation responsible for the
evolution of differences within a single species. Among
humans, for example, different populations can show distinct
physical characteristics, disease susceptibility, and
lifestyle adaptations such as the ability to digest
lactose. Other differences can be more extreme, as seen in a
population of house mice found on remote Gough Island in the
south Atlantic. In just 200 years of isolation, the Gough
Island mice have become twice as large as their mainland
counterparts and are also the only known carnivorous mice in
the world, preying on seabird chicks and driving at least
one species, the Tristan albatross, toward
extinction. Payseur is currently working to understand the
evolutionary history of this unusual mouse
population. CONTACT: Bret Payseur, 608-890-0867,
[email protected]
Invasive species: Evolving a path to success
In the rough-and-tumble world of biology, a tiny fraction
of species have developed a very useful trick: the ability
to invade and make themselves at home in environments very
unlike their home turf. For example, zebra and quagga
mussels native to Eurasia normally thrive in saline or
brackish water but have established freshwater populations
in the U.S. Great Lakes. They are so successful that they
now threaten our native freshwater ecosystems and are
driving native mussels to extinction. Evolutionary
geneticist Carol Lee calls such species "weedy" for the
ability to spread and thrive under a variety of
environmental conditions. Her research as an associate
zoology professor focuses on two main questions: What traits
allow some populations to invade new habitats, and how do
such traits evolve? In addition to the mussels, she studies
an invasive species of copepod, a tiny crustacean that has
also made the leap from salt to fresh water. She is working
to identify the genes and types of mutations that allow such
invasive species to adapt so readily to different
conditions. Understanding species' evolutionary potential
may also hold the key to predicting how species will respond
to environmental and climate changes. CONTACT: Carol Lee,
608-262-2675, [email protected]
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