Voyager Therapeutics Presents New Data Supporting Tau Antibody Program for Alzheimer's Disease and GBA1 Gene Therapy Program for Parkinson's Disease at the AD/PD™ Conference
CAMBRIDGE, Mass., March 28, 2023 (GLOBE NEWSWIRE) -- Voyager Therapeutics, Inc. (Nasdaq: VYGR), a biotechnology company dedicated to breaking through barriers in gene therapy and neurology, today presented new data from its anti-tau antibody program for Alzheimer’s disease (AD) and from its GBA1 gene therapy program for Parkinson’s disease (PD) and other GBA1-mediated diseases at the AD/PD™ Conference in Gothenburg, Sweden.
“Voyager continues to advance multiple programs towards the clinic. For our anti-tau antibody program for Alzheimer’s disease, these new preclinical data support our recent selection of VY-TAU01 as the lead development candidate, with an IND filing expected in the first half of 2024,” said Todd Carter, Ph.D., Chief Scientific Officer at Voyager. “For our GBA1 gene therapy program with Neurocrine for Parkinson’s disease, these new data from a GBA1 loss of function mouse model show effects of three GBA1 gene therapy candidates on multiple endpoints.”
Selection of an Anti-tau Antibody Candidate Targeting Pathological Tau for the Treatment of Alzheimer's Disease (Wencheng Liu, Poster P0643 / #1192)
Development of AAV-GBA1 gene replacement therapy via single-IV-delivery with a blood brain barrier penetrant AAV capsid (Charlotte Chung, April 1, 2023, 11:55 CET, #1696)
About Voyager Therapeutics
Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc.
For example, all statements Voyager makes regarding preclinical data for its antibody programs and AAV-based gene therapy programs, including the presentation of preclinical data at the 2023 AD/PD Conference; Voyager’s ability to continue to identify and develop anti-tau antibodies; Voyager’s ability to develop its tau antibody program; Voyager’s ability to continue to identify and develop proprietary capsids from its TRACER capsid discovery platform with increased transgene expression, increased blood-brain barrier penetration and increased biodistribution compared to conventional AAV9 and AAV5 capsids; Voyager’s ability to utilize its novel proprietary capsids in its own product development programs; Voyager’s ability to advance its AAV-based gene therapy programs; the preclinical development of its potential development candidates; and Voyager’s ability to utilize its TRACER capsids and antibodies in its product development programs are forward looking.
All forward-looking statements are based on estimates and assumptions by Voyager’s management that, although Voyager believes such forward-looking statements to be reasonable, are inherently uncertain. All forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those that Voyager expected. Such risks and uncertainties include, among others, the continued development of Voyager’s technology platforms, including Voyager’s TRACER platform and its antibody screening technology; the ability to initiate and conduct preclinical studies in pre-clinical animal models; the development by third parties of capsid identification platforms that may be competitive to Voyager’s TRACER capsid discovery platform; Voyager’s ability to create and protect intellectual property rights associated with the TRACER capsid discovery platform, the capsids identified by the platform and Voyager’s pipeline developmental programs; the initiation, timing, conduct and outcomes of Voyager’s preclinical studies; the ability to attract and retain talented contractors and employees; and the sufficiency of cash resources to fund its operations and pursue its corporate objectives.
These statements are also subject to a number of material risks and uncertainties that are described in Voyager’s most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission. All information in the press release is as of the date of this press release, and any forward-looking statement speaks only as of the date on which it was made. Voyager undertakes no obligation to publicly update or revise this information or any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law.