Araris Biotech AG to Present at the 22nd Annual PepTalk: Protein Science and Production Week
ZURICH, Switzerland, Jan. 19, 2023 (GLOBE NEWSWIRE) -- Araris Biotech AG, a company pioneering a proprietary antibody-drug conjugate (ADC)-linker technology, today announced that Bernd Schlereth, Ph.D., chief development officer, will deliver an oral presentation at the 22nd annual PepTalk: Protein Science and Production Week being held January 16- 20, 2023 in San Diego. During the event’s “Bispecific Antibody Development” program, Dr. Schlereth will present positive data showing that Araris’ CD79b-targeting antibody-drug conjugate (ADC), ARC-02, has demonstrated improved efficacy and safety compared to the approved ADC polatuzumab-vedotin (Polivy®) in non-human primate and rodent models of non-Hodgkin lymphoma (NHL).
“These data demonstrate the sophistication of our proprietary linker technology and its ability to precisely synthesize homogeneous, stable and effective ADC therapies in preclinical models,” said Philipp Spycher, Ph.D., chief executive officer and co-founder of Araris Biotech. “Our in vitro and in vivo data suggest that ARC-02, which uses the same antibody and payload as Polivy® but is assembled with Araris’ linker technology, confers an improved therapeutic index. We look forward to continuing to study the potential of this therapeutic to better help patients.”
Speaker: Bernd Schlereth, Ph.D.
Date/Time: January 20, 2023, 9:35 a.m. PST
Data highlights include:
About Araris Biotech AG
Araris Biotech AG is pioneering the development of its novel antibody-drug conjugate (ADC)-linker technology to enable efficient and precise production of ADCs. Its linker platform enables the attachment of any drug payload to ‘off the shelf’ antibodies, without the need for prior antibody engineering. The resulting ADCs have shown very high activity at low doses and an improved therapeutic index compared to FDA-approved ADCs. Araris is a spin-off company from the Paul Scherrer Institute (PSI) and ETH Zurich.
For more information, please visit www.ararisbiotech.com or follow Araris on Twitter and LinkedIn.