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Recent Peer-Reviewed Publication Supports Immunotherapy for the Treatment of Food AllergiesNEW YORK, Oct. 08, 2020 (GLOBE NEWSWIRE) -- A recent publication in the journal Immunotherapy reviews a variety of immunotherapy platforms for the treatment of food allergies. The article, “Sublingual immunotherapy for food allergy and its future directions,” reviews the potential of Sublingual Immunotherapy (SLIT) options.1 SLIT for food allergy involves placement of glycerinated allergen under the tongue daily to achieve allergen-specific desensitization. According to the authors, SLIT has been studied in the treatment of hazelnut, peach, apple, milk and peanut allergies with substantial focus on the treatment of peanut allergy. Phase II studies have shown SLIT for treatment of peanut allergy increases the tolerated dose of peanut by a substantial margin with fewer and less severe side effects than other modalities. “We are excited about the publication of this comprehensive review of immunotherapy options for food allergies,” said William Reisacher, MD, Senior Scientific Advisor, Intrommune Therapeutics. “We are confident that allergy desensitization using an oral mucosal immunotherapy (OMIT) toothpaste may deliver specific allergens more effectively than SLIT.” Intrommune’s lead OMIT product, INT301, is being developed for the treatment of peanut allergies. INT301’s unique OMIT formulation is designed to desensitize an individual with peanut allergy using a toothpaste delivery system, protecting them in the event of accidental peanut exposure. The authors reference a study by Reisacher, et al., which compares 24 patients receiving either SLIT or OMIT for multiple allergies. In this study, adherence -- which was defined as received over 90% of doses over a 12-month period -- was 80% in OMIT and 62% in SLIT.2 “The use of a patented toothpaste delivery platform is expected to improve allergy immunotherapy by increasing the precision of treatment delivery and promoting treatment adherence,” said Erick Berglund, PhD, Chief Scientific Officer. “OMIT delivers immunotherapy to the oral mucosa, which has the highest likelihood of initiating allergy desensitization. Targeted delivery of medication is expected to decrease the rate of side effects linked to swallowing food allergy proteins, including eosinophilic esophagitis, gastrointestinal discomfort and potentially life-threatening anaphylaxis that requires the use of emergency epinephrine.” Abou Peanut and Other Food Allergies About Oral Mucosal Immunotherapy About Intrommune Therapeutics The Keiretsu Forum, a global investment community of accredited angel investors, has engaged in a thorough diligence process with Intrommune and has issued a positive report. To access this report, please visit: http://www.intrommune.com/keiretsu-dd. For more information on Intrommune Therapeutics, please visit http://www.intrommune.com This release may contain "forward-looking statements." Forward-looking statements are identified by certain words or phrases such as "may," "will," "aim," "will likely result," "believe," "expect," "will continue," "anticipate," "estimate," "intend," "plan," "contemplate," "seek to," "future," "objective," "goal," "project," "should," "will pursue" and similar expressions or variations of such expressions. These forward-looking statements reflect the company's current expectations about its future plans and performance. These forward-looking statements rely on a number of assumptions and estimates which could be inaccurate, and which are subject to risks and uncertainties. Actual results could vary materially from those anticipated or expressed in any forward-looking statement made by the company. The company disclaims any obligation or intent to update the forward-looking statements in order to reflect events or circumstances after the date of this release. This release does not contain or constitute an offer to sell or a solicitation of any offer to buy securities in the United States or in any other jurisdiction. Contact:
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