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Luma Therapeutics Announces Launch of the Illuvinate System, a New In-Home Treatment for Plaque Psoriasis
[December 05, 2018]

Luma Therapeutics Announces Launch of the Illuvinate System, a New In-Home Treatment for Plaque Psoriasis


Luma Therapeutics, a company dedicated to eradicating suffering from inflammatory skin disease, today announced the launch of an innovative light-based therapy for the treatment of plaque psoriasis. The company's FDA-cleared breakthrough technology, the illuvinate™ System, is an in-home treatment designed to provide lasting relief from psoriasis symptoms. Illuvinate can now be prescribed either by a dermatologist or via Luma's telehealth provider, HealthLens.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20181205005217/en/

The illuvinate™ System, an in-home treatment designed to provide lasting relief from psoriasis sympt ...

The illuvinate™ System, an in-home treatment designed to provide lasting relief from psoriasis symptoms. (Photo: Business Wire)

Psoriasis - an inflammatory condition resulting in painful, raised patches of skin often found on the scalp, knees, elbows, and lower back - affects two to three percent of the world's population and 7.5 million people in the U.S. alone. In addition to the discomfort and embarrassment endured by psoriasis sufferers, the condition is associated with depression, cardiovascular disease and Type II diabetes.1

Luma Therapeutics was founded with a vision to end the suffering of patients with inflammatory skin conditions, starting with psoriasis.

"As a psoriasis sufferer, I knew how important it was to find a better solution than what was currently available," said founder and CEO Evan Anderson. "We are pleased that the illuvinate System is now available to help people in California with psoriasis, a condition that often has a serious impact on quality of life. We look forward to launching nationally next year."

Current common treatments for psoriasis fall short: topical steroid treatments can be messy and ineffective, and many patients are reluctant to take medications that may have long-term side effects. Other treatments are only available in a clinical setting, presenting an obstacle to consistent adherence.

The most effective treatment for psoriasis is the Goeckerman Regimen, a 100-year-old proven therapy that results in long periods of remission lasting between eight months to over a year.2 However this treatment is only available at a handful of specialized academic centers and often requires multiple day-long clinic visits over a period of weeks, creating barriers to widespread adoption. Luma Therapeutics has redesigned the key elements of the Goeckerman Regimen to make it available to patients in their own home.



Jeffrey Sugarman, M.D., Ph.D., of Redwood Family Dermatology in Santa Rosa, Calif., and UCSF Health in San Francisco, serves as Luma Therapeutic's Chief Medical Officer and principal investigator of studies of the illuvinate System.

"Psoriasis is a chronic condition for which there is no cure, and there is a need for better treatment options. Most available treatments require ongoing compliance in order to achieve optimal results, and many patients are hesitant to consistently use medications, which may have long-term side effects, " said Dr. Sugarman. "As a result, patients become discouraged and stop seeking treatment from a dermatologist. I believe that the illuvinate System will be a great option for many patients."


Dr. Sugarman's patient Georgios Kladis participated in the clinical trials of the system.

"I have had psoriasis for many years and have tried all kinds of psoriasis treatments, and none of them worked. The illuvinate System cleared my skin quickly," said Georgios. "Even more exciting was how long my skin stayed clear after the treatment. I like that it does not involve the side effects of a drug and takes just minutes a day in my home. I would recommend it to other people dealing with psoriasis."

Illuvinate has been demonstrated to reduce local inflammation, rehydrate the skin and restore normal skin cells. The system includes patented hydrating technology, a narrowband UV LED light system, and a proprietary app-based dosing algorithm. The therapy is applied for just minutes each day over a six-week period from the comfort and convenience of home.

"We are excited to partner with Luma Therapeutics to offer the illuvinate System to psoriasis patients," said Christopher Schmidt, M.D., board-certified dermatologist and founder of HealthLens, a multi-specialty telemedicine platform, as well as a clinical faculty member of Stanford University. "Telehealth is the next frontier in medicine, enabling patients easy access to treatments that can dramatically improve their condition and quality of life. Dermatology is uniquely suited to telehealth. In fact, recent research concluded that an online, collaborative health model was as effective as in-person management in improving clinical outcomes among patients with psoriasis."3

About Luma Therapeutics

Based in Silicon Valley, Luma Therapeutics is a privately held medical technology company committed to developing innovative and convenient therapies for the millions of people around the world suffering from inflammatory skin disease. In collaboration with Mayo Clinic, Luma Therapeutics developed the FDA-cleared illuvinate™ System to offer patients with psoriasis an effective treatment option that can be used at home. The company has also been supported by StartX accelerator and the Rosenman Institute at QB3. For more information visit https://illuvinate.com/.

About HealthLens

HealthLens provides medical device companies with custom telemedicine solutions to access large numbers of patients and providers without the need for a traditional sales force. For more information visit www.HealthLens.com.

1 "Comorbidities Associated with Psoriatic Disease." National Psoriasis Foundation, www.psoriasis.org/about-psoriasis/related-conditions.

2 Gupta, Rishu, et al. "The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis." Journal of Visualized Experiments, no. 77, 2013, doi:10.3791/50509.

3 Armstrong, W. "Online vs In-Person Care for Adults With Psoriasis." JAMA, American Medical Association, 5 Oct. 2018, jamanetwork.com/journals/jamanetworkopen/fullarticle/2705854.


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