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Hemispherx Notes the Importance of Immunizations During Upcoming National Immunization Awareness Month and Potential of Ampligen in Influenza Vaccine StrategiesORLANDO, Fla., July 03, 2018 (GLOBE NEWSWIRE) -- Hemispherx Biopharma, Inc. (NYSE American:HEB), an immuno-pharma R&D company focused on unmet medical needs in immunology, is pleased to enthusiastically support National Immunization Awareness Month (NIAM), which is observed annually during August. NIAM is designed “to celebrate the benefits of vaccination and highlight the importance of vaccination for people of all ages,” according to its sponsor, the National Public Health Information Coalition. To learn more about NIAM, please click here. Hemispherx’s reaffirms its commitment to R&D progress in this space which is of critical importance to public health. Hemispherx is confident about the potential role of Ampligen, one of its patented core technologies, in treating or preventing a range of immune mediated diseases, including influenza. One key area of on-going Hemispherx research is the development of a “universal” influenza vaccine which, would provide multi-year protection against not only seasonal influenza strains, but also those with the potential to cause lethal global dipandemics. Ampligen is a selective toll-like receptor 3 agonist capable of inducing innate and adaptive immune responses. In a human intranasal vaccine study of Ampligen plus FluMist, the combination was shown to be well-tolerated. Moreover, patients in the Ampligen plus FluMist treatment group produced antibodies against highly lethal avian influenza viruses including H5N1 and H7N9 that were not present in the immunizing vaccines. Pathogenic avian strains of influenza with high mortality in humans remain a clear and present human danger of being spread by potentially devastating influenza pandemics. Hideki Hasegawa, MD, Director, Department of Pathology (National Institute of Infectious Diseases, Japan) stated, “Our experimental findings in rodents and non-human primates using intranasal vaccination clearly showed that Ampligen enhanced the activity of influenza vaccines by conferring increased cross-reactivity and cross-protection, even with deady avian H5N1 influenza viruses. Such effects will be key to the development of a universal vaccine for influenza.” Edgar Turner Overton, MD, Associate Professor, Division of Infectious Diseases, University of Alabama School of Medicine stated, “Building on the work of Dr. Hasegawa, we studied intranasal Ampligen administration following influenza vaccine clinically. The Ampligen was well-tolerated and evidence for cross-reactivity against avian influenza strains was also seen in humans.” “The opportunity to develop a globally effective influenza vaccine is an important part of our overall development strategy for Ampligen,” said David R. Strayer, MD, Chief Science and Medical Officer of Hemispherx. “Studies conducted on the activity of Ampligen in combination with influenza vaccines suggest that intranasal immunization with Ampligen as an adjuvant may provide an effective and well-tolerated means of protecting at-risk humans.” The global influenza vaccine market is estimated to exceed $3 billion in 2018, according to the World Health Organization. It is projected to achieve a compound annual growth rate of 6.93% from 2017 to 2023, to reach $4.6 billion by 2023, up from an anticipated $3 billion in 2018, according to market research firm Research and Markets. “Hemispherx is seriously exploring co-development partnerships with influenza vaccine producers. Our goal is to make a positive difference in viral vaccines, both in terms of enhanced effectiveness and cross-reactivity and cross-protection. We have focused our R&D on three key areas, immuno-oncology, ME/CFS, and vaccine enhancement. Our belief is strong that our vaccine work can and will make an important difference for improved public health in the future,” states Tom Equels, CEO at Hemispherx. About Hemispherx Biopharma Cautionary Statement Contact |