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Farxiga (dapagliflozin; AstraZeneca) Drug Analysis 2017 - ResearchAndMarkets.comThe "Drug analysis: Farxiga" drug pipelines has been added to ResearchAndMarkets.com's offering. Farxiga (dapagliflozin; AstraZeneca) is a member of the novel sodium-glucose cotransporter-2 (SGLT-2) inhibitor class. It is approved for the treatment of type 2 diabetes and currently in Phase III trials for the treatment of type 1 diabetes. SGLT-2 inhibitors do not target insulin secretion or sensitivity and do not interfere with glucose metabolism. They prevent filtered glucose from being reabsorbed in the kidney rather than actively facilitating glucose filtration and excretion. Due to this distinct mechanism of action, when SGLT-2 inhibitors are used as monotherapy, they do not lower glucose to unsafe levels and thus avoid the risk of hypoglycemia. The drug was developed as part of a joint venture between AstraZeneca and Bristol-Myers Squibb. However, AstraZeneca has taken full ownership and marketing responsibilities ater buying its partner's share of the venture. Key Topics Covered: List of Figures Figure 1: Farxiga for type 2 diabetes - SWOT analysis Figure 2: Drug assessment of Farxiga Figure 3: Drug assessment scorecard for Farxiga compared to Januvia Figure 4: Farxiga sales for type 2 diabetes across the US, Japan, and five major EU markets, by country, 2016-25 Figure 5: Xigduo sales for type 2 diabetes across the US, Japan, and five major EU markets, by country, 2016-25 Figure 6: Farxiga for type 1 diabetes - SWOT analysis Figure 7: Drug assessment of Farxiga in type 1 diabetes Figure 8: Drug assessment of Farxiga in type 1 diabetes List of Tables Table 1: Farxiga franchise products Table 2: Farxiga drug profile Table 3: Xigduo drug profile Table 4: Overview of pivotal trial data for Farxiga in diabetes Table 5: Key planned and ongoing Phase III clinical trials for Farxiga in diabetes Table 6: Farxiga sales for type 2 diabetes across the US, Japan, and five major EU markets, by country ($m), 2016-25 Table 7: Xigduo sales for type 2 diabetes across the US, Japan, and five major EU markets, by country ($m), 2016-25 Table 8: Farxiga drug profile Table 9: Farxiga late-phase trial in type 1 diabetes For more information about this drug pipelines report visit https://www.researchandmarkets.com/research/xjhhqh/farxiga?w=4 View source version on businesswire.com: http://www.businesswire.com/news/home/20180220006294/en/ |