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Global 20s Proteasome Pipeline Report 2016 - Therapeutics Activities of Amgen Inc & LG Life Science - Research and MarketsResearch and Markets has announced the addition of the "20s Proteasome - Pipeline Review, H1 2016" drug pipelines to their offering. 20s Proteasome pipeline Target (News - Alert) constitutes close to 8 molecules. Out of which approximately 8 molecules are developed by Companies. Our latest report 20s Proteasome - Pipeline Review, H1 2016, outlays comprehensive information on the 20s Proteasome targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. 20s Proteasome 20S proteasome is the catalytic core of the 26S proteasome, the central protease of the ubiquitin pathway of protein degradation. It is commonly associated with regulatory complexes, which include the 19S Proteasome, the PA28 alpha/beta complex, or the PA28 gamma complex. The 20S Proteasome is composed of 28 subunits arranged into four stacked ings. Unlike the 26S proteasome, which degrades proteins in an ATP (News - Alert)-dependent manner, the 20S proteasome is ATP-independent and only degrades entirely unfolded polypeptides. The molecules developed by Companies in Pre-Registration, Phase II, Preclinical and Discovery stages are 1, 2, 3 and 2 respectively. Furthermore, this report also reviews key players involved in 20s Proteasome targeted therapeutics development, features dormant and discontinued projects and latest news and press releases. Key Topics Covered:
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