[February 11, 2016] |
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10x Genomics' New Chromium™ System Enables Full Access to Critical Molecular and Cellular Information
10x
Genomics today introduced the new Chromium System, a transformative
upgrade for existing short-read sequencers. The Chromium System unlocks
critical long range genomic and cell-by-cell gene expression
information. The system supports the following applications:
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Chromium Single Cell 3' performs deep profiling of complex cell
populations with high-throughput digital gene expression on a
cell-by-cell basis. Tracing expression profiles to individual cells
ensures biologically relevant signals are not masked by bulk average
measurements.
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Chromium Genome provides long-range information on a
genome-wide scale, including variant calling, phasing and extensive
characterization of genomic structure, enabling identification of
critical variants in heritable disorders and discovery of key
alterations in cancer.
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Chromium Exome provides long-range information for phasing,
structural variant detection and copy number determination, giving
researchers access to low-complexity and repetitive regions previously
missed with shortread sequencing.
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The Supernova™ Assembler opens the door to low-cost, everyday
diploid de novo assemblies by unlocking sample-specific
sequence and produces diploid genome structure.
"The Genomics Platform at the Broad Institute has obtained exciting
results for multiple applications using the GemCode™ technology from 10x
Genomics," said Dr. Stacey Gabriel from the Broad Institute of MIT (News - Alert) and
Harvard.
10x Genomics will be sharing more details about the new system at the
Advances in Genome Biology and Technology (AGBT) conference currently in
progress. Dr. Gabriel and Dr. Scott Furlan from the University of
Washington will be sharing compelling results during the 10x seminar on
Friday, Feb. 12. Several additional customers will be presenting their
exciting discoveries with powerful Linked-Read data throughout the
conference.
Serge Saxonov, Ph.D., CEO and Founder of 10x Genomics, commented, "We
are extremely proud to introduce the Chromium System, which provides the
benefits of GemCode technology, including long range information,
megabase-scale phasing, uniform coverage, and structural variant
detection while integrating single cell sequencing into the same system.
Single cell sequencing provides customers access to yet another cutting
edge capability. Finally, our new de novo assembler represents
the true genome."
The Chromium System is delivered ready to run, with reagents,
consumables, and turnkey software for analyzing and visualizing data and
is compatible with all major Illumina sequencers including the HiSeq XTM
Ten.
About 10x Genomics 10x Genomics meets the critical need for
long range, structural and cellular information, with an innovative
system that transforms the capability of existing short-read sequencers.
10x Genomic's Chromium™ System supports comprehensive genomics and
high-throughput single cell transcriptomics. It enables researchers to
discover previously inaccessible genomic information at unprecedented
scale, including phased structural variants, phased single nucleotide
variants, and dynamic gene expression of individual cells-while
leveraging their existing sequencing systems and workflows.
View source version on businesswire.com: http://www.businesswire.com/news/home/20160211005337/en/
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