[August 28, 2014]

Eleven Biotherapeutics to Participate in Upcoming Investor Conferences in September

Eleven Biotherapeutics (NASDAQ: EBIO), a biopharmaceutical company discovering and developing protein therapeutics to treat diseases of the eye, today announced that Abbie Celniker, Ph.D., President and Chief Executive Officer, will participate in the following upcoming investor conferences in September:

• Citi 9^th Annual Biotech Conference in Boston on Thursday, September 4, 2014. Management will participate in a panel discussion entitled "Emerging Ophthalmology Therapies: Getting 20/20 on the Drug Landscape" at 12:00 p.m. E.T.
• NewsMakers in the Biotech Industry Conference in New York on Friday, September 26 2014. Management will present a corporate overview at 11:00 a.m. ET.

About Eleven Biotherapeutics

Eleven Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company with a proprietary protein engineering platform, called AMP-Rx, that it applies to the discovery and development of protein therapeutics to treat diseases of the eye. The Company's therapeutic approach is based on the role of cytokines in diseases of the eye, the Company's understanding of the structural biology of cytokines and the Company's ability to rationally design and engineer proteins to modulate the effects of cytokines. Cytokines are cell signaling molecules found in the body that can have important inflammatory effects.

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