| [February 14, 2012] |
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TRADE NEWS: Agilent Technologies Extends Target-Enrichment Platform to Desktop Sequencers
MARCO ISLAND, Fla. --(Business Wire)--
(AGBT)--Agilent Technologies (News - Alert) Inc. (NYSE:A) today expanded its SureSelect
target-enrichment system with the HaloPlex
target enrichment system for desktop sequencers. The product will be
unveiled at the Advances in Genome Biology and Technology meeting here
tomorrow.
Exclusive HaloPlex technology combines the speed and specificity of
polymerase chain-reaction systems with the scalability and capture-size
flexibility of in-solution hybridization formats. The library prep-free
single tube protocol overcomes the target-number limitations of
multiplex PCR (News - Alert) due to cross-hybridization issues, reduces sample prep
time to less than one day, and is compatible with Illumina MiSeq desktop
sequencers as well as HiSeq and GAIIx sequencers.
"While next-generation sequencing has made the analysis of complete
genomes possible, often we have more targeted questions where we want to
survey small sets of genes in large numbers of individuals," said Edwin
Cuppen, principal investigator, Genome Biology, Hubrecht Institute. "For
the range of a few to dozens of genes, current hybrid capture enrichment
technologies have their limitations. HaloPlex technology very nicely
fills this gap nd makes it possible for us to capture the complete
coding sequences of two to 20 genes in a single reaction. This is with
efficiency of more than 90 percent of reads on-target.
"The combined application of HaloPlex enrichment technology with Ion
Torrent semiconductor sequencing provides a versatile and rapid setup
for high-throughput, small-footprint target gene resequencing."
Dr. Cuppen is part of Agilent's Early Access program for HaloPlex
compatibility with Ion Torrent platforms.
"This is just one example of our aggressive product development program
to strengthen SureSelect's leadership position," said Olle Ericsson (News - Alert),
founder of Halo Genomics and now Agilent director of marketing, DNA
Sequencing. "In just two years since its launch, SureSelect has been
cited as playing a key role in more than 200 major published studies.
HaloPlex is an innovative technology that puts Agilent ahead of the
curve as desktop sequencing and target enrichment move into clinical
research."
HaloPlex is a customizable product that enables users to create designs
to enrich thousands of genomic targets in less than 10 minutes using the
free Web Design Wizard.
Agilent obtained the product in December 2011 with the acquisition of
Halo Genomics of Uppsala, Sweden. HaloPlex technology is a perfect
complement to the Agilent SureSelect target-enrichment system. The new
product now also benefits from Agilent's R&D, manufacturing and
distribution resources.
For more information, visit www.agilent.com/genomics/ngs.
About Agilent Technologies
Agilent Technologies Inc. (NYSE: A) is the world's premier measurement
company and a technology leader in chemical analysis, life sciences,
electronics and communications. The company's 18,700 employees serve
customers in more than 100 countries. Agilent had net revenues of $6.6
billion in fiscal 2011. Information about Agilent is available at www.agilent.com.
NOTE TO EDITORS: Further technology, corporate citizenship and executive
news are available at www.agilent.com/go/news.
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