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The International Myeloma Foundation Says Three Studies Highlighting Myeloma Treatment-Advances Are Featured Together in the Prestigous New England Journal of Medicine
NORTH HOLLYWOOD, Calif. --(Business Wire)--
The International Myeloma Foundation (IMF) - the oldest and largest
foundation dedicated to improving the life and care of myeloma patients
- says three studies demonstrating that long term maintenance treatment
"significantly improves outcome" and more than doubles remission times,
have been published together in the New England Journal of Medicine. The
articles cover the use of continuous treatment with the oral drug
REVLIMID© both in newly diagnosed patients and following stem
cell transplants. Although the findings have been presented separately
at medical conferences this marks their first publication together in a
scientific "peer reviewed" journal, an indication of the importance of
these findings.
Myeloma, often called multiple myeloma, is a disease of cells in the
bone marrow. Newer treatments can result in lengthy remissions, and in
the current issue of the New England Journal of Medicine studies
demonstrate additional progress:
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Two studies, one from France and one from the United States,
demonstrated that maintenance treatment with REVLIMID following a
stem cell transplant using their own cells (autologous) cut by more
than half the time until the disease began to progress again, and
the U.S. study reports the treatment improves overall survival.
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A third study from Italy demonstrated that in patients over 65, not
generally eligible for a transplant, REVLIMID used in the initial
treatment, followed by REVLIMID in a maintenance regimen, also
reduced by more than half the time until the disease progressed, and
improved survival: 70% survival at 3 years with this treatment
compared to 62% without the maintenance.
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"The development of new, targeted drugs that are well tolerated allow us
to continue treatment long term, which was not possible with the earlier
harsh forms of chemotherapy," said Brian G.M. Durie, M.D., Co-founder
and Chairman of the IMF. "The published data on maintenance give us the
hope that this can become a standard of care."
The studies were conducted by the Cancer and Leukemia Group B (CALGB)
study sponsored by the U.S. National Cancer Institute, the French
Francophone Myeloma Intergroup (IFM), and from University of Torino in
Italy.
The novel therapies, including REVLIMID and VELCADE©, have
transformed the treatment of myeloma. With studies such as these doctors
are finding new and even better ways to utilize these treatment advances.
ABOUT THE INTERNATIONAL MYELOMA FOUNDATION
Celebrating its 21st anniversary, the International Myeloma
Foundation is the oldest and largest myeloma organization, reaching more
than 215,000 members in 113 countries worldwide. A 501 (c) 3 non-profit
organization dedicated to improving the quality of life of myeloma
patients and their families, the IMF focuses on four key areas:
research, education, support, and advocacy. To date, the IMF has
conducted more than 250 educational seminars worldwide, maintains a
world-renowned hotline, and established the International Myeloma
Working Group (IMWG), a collaborative research initiative focused on
improving myeloma treatment options for patients. The IMF can be reached
at (800) 452-CURE (2873). The global website is www.myeloma.org

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