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BIO Releases Report on State of Innovation for Pain and Addiction TherapeuticsToday, the Biotechnology Innovation Organization (BIO) released a new report, The State of Innovation in Highly Prevalent Chronic Diseases: Pain and Addiction Therapeutics. While many promising treatment approaches are in development, lower investment and pipeline breadth in pain and addiction relative to other disease areas with high societal health burdens demonstrates the need for incentivizing more research and clinical development in these areas. "America's biopharmaceutical companies are committed to combating our nation's opioid epidemic," said BIO President and CEO Jim Greenwood. "This will depend upon biomedical innovation and the development of novel and safer, next generation therapies to treat both pain and addiction, which together cost our country more than $1 trillion annually. While there are promising technologies under development, more must be done to stimulate research and development for these areas of high unmet need." The report analyzed the last decade of clinical trial activity, FDA approvals, and venture investment as well as the breadth and depth of the current pipeline for novel therapies in pain and addiction. Key Takeaways
"On the surface, 125 clinical-stage-programs utilizing 20 unique mechanistic strategies sounds impressive. However, with a success rate over the last decade of a mere 2 percent, only a few of these may actually reach FDA approval. As some of these future successes may be specific for chronic migraine and indications where opioids are not prescribed, more shots on goal are needed to fill the void in chronic pain," said report author David Thomas, Senior Director, Industry Research & Policy Analysis for BIO. "The addiction pipeline has 10-fold fewer clinical-stage programs than pain, suggesting a need for incentivizing innovation in this space." The report - The State of Innovation in Highly Prevalent Chronic Diseases: Pain and Addiction - is available for download here: www.bio.org/iareports. About BIO BIO is the world's largest trade association representing biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. BIO also produces the BIO International Convention, the world's largest gathering of the biotechnology industry, along with industry-leading investor and partnering meetings held around the world. BIOtechNOW is BIO's blog chronicling "innovations transforming our world" and the BIO Newsletter is the organization's bi-weekly email newsletter. Subscribe to the BIO Newsletter. Upcoming BIO Events
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